Results 41 to 50 of about 33,094 (123)

Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro

Mediators of Inflammation, 2020
Alzheimer's disease (AD) is a common neurodegenerative disease. Aβ plays an important role in the pathogenesis of AD. Sodium butyrate (NaB) is a short-chain fatty acid salt that exerts neuroprotective effects such as anti-inflammatory, antioxidant ...
Jingxuan Sun, Boyu Yuan, Yancheng Wu, Yuhong Gong, Wenjin Guo, Shoupeng Fu, Yongxin Luan, Wei Wang   +7 more
semanticscholar   +1 more source

Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Polyphenols, ω3 and ω9 Unsaturated Fatty Acids) of the Mediterranean Diet on N2a Neuronal Cells

Molecules, 2020
The brain, which is a cholesterol-rich organ, can be subject to oxidative stress in a variety of pathophysiological conditions, age-related diseases and some rare pathologies.
A. Yammine, T. Nury, A. Véjux, N. Latruffe, D. Vervandier-Fasseur, M. Samadi, H. Greige‐Gerges, L. Auezova, G. Lizard   +8 more
semanticscholar   +1 more source

Analysis of immune, microbiota and metabolome maturation in infants in a clinical trial of Lactobacillus paracasei CBA L74-fermented formula

Nature Communications, 2020
Mother’s milk is the best choice for infants nutrition, however when it is not available or insufficient to satisfy the needs of the infant, formula is proposed as an effective substitute.
P. Roggero, N. Liotto, C. Pozzi, D. Braga, J. Troisi, Camilla Menis, M. Giannì, R. Berni Canani, L. Paparo, R. Nocerino, A. Budelli, F. Mosca, M. Rescigno   +12 more
semanticscholar   +1 more source

N2A Titin: Signaling Hub and Mechanical Switch in Skeletal Muscle

International Journal of Molecular Sciences, 2020
Since its belated discovery, our understanding of the giant protein titin has grown exponentially from its humble beginning as a sarcomeric scaffold to recent recognition of its critical mechanical and signaling functions in active muscle.
K. Nishikawa, S. Lindstedt, A. Hessel, Dhruv Mishra   +3 more
semanticscholar   +1 more source

ISEV2018 abstract book

, 2018
Journal of Extracellular Vesicles, Volume 7, Issue S1, April 2018.
Clotilde Théry, Kenneth Witwer
wiley   +1 more source

Single-Molecule Force Spectroscopy on the N2A Element of Titin: Effects of Phosphorylation and CARP

Frontiers in Physiology, 2020
Titin is a large filamentous protein that forms a sarcomeric myofilament with a molecular spring region that develops force in stretched sarcomeres. The molecular spring has a complex make-up that includes the N2A element.
Thomas Lanzicher, Tiankun Zhou, Chandra Saripalli, Vic Keschrumrus, John E Smith Iii, O. Mayans, O. Sbaizero, H. Granzier   +7 more
semanticscholar   +1 more source

Geographical distribution, molecular and toxin diversity of the dinoflagellate species Gambierdiscus honu in the Pacific region.

, 2023
An increase in cases of ciguatera poisoning (CP) and expansion of the causative species in the South Pacific region highlight the need for baseline data on toxic microalgal species to help identify new areas of risk and manage known hot spots ...
Argyle, P, Chinain, M, Darius, HT, De Azevedo, CD, Henry, K, Murray, JS, Murray, SA, Rhodes, L, Smith, KF, Stuart, J, Viallon, J   +10 more
core   +1 more source

Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke

Brain and Behavior, 2018
Curcumin, a natural antioxidant isolated from Curcuma longa, has been reported to exert neuroprotective effect in animal models of ischemic stroke. However, the underlying mechanism is still not fully understood.
Caijun Xie, Ai-ping Gu, Jun Cai, Yi Wu, Rui-Cong Chen   +4 more
semanticscholar   +1 more source

Detección de toxinas marinas y caracterización de su mecanismo de acción mediante ensayos celulares. Aplicaciones a la identificación de riesgos alimentarios [PDF]

, 2015
Les intoxicacions alimentàries degudes a toxines marines suposen un problema de salut públic i té un gran impacte econòmic sobre el sector pesquer. Els nivells de toxines marines que estan permesos en els productes pesquers i els mètodes d'anàlisi d ...
Soliño Alonso, Lucía
core   +1 more source

Calcium increases titin N2A binding to F-actin and regulated thin filaments

Scientific Reports, 2018
Mutations in titin are responsible for many cardiac and muscle diseases, yet the underlying mechanisms remain largely unexplained. Numerous studies have established roles for titin in muscle function, and Ca2+-dependent interactions between titin and ...
S. Dutta, C. Tsiros, SaiLavanyaa Sundar, H. Athar, Jeffrey R. Moore, Brent Nelson, M. Gage, K. Nishikawa   +7 more
semanticscholar   +1 more source