Results 51 to 60 of about 33,094 (123)

Rice flour fermented with Lactobacillus paracasei CBA L74 in the treatment of atopic dermatitis in infants: A randomized, double- blind, placebo- controlled trial.

open access: yesPharmacological Research, 2020
To assess the effect of a fermented rice-flour obtained from Lactobacillus paracasei CBA L74 in managing infants with moderate to severe atopic dermatitis.
E. D’Auria   +13 more
semanticscholar   +1 more source

ISEV2019 Abstract Book

open access: yes, 2019
Journal of Extracellular Vesicles, Volume 8, Issue S1, April 2019.
wiley   +1 more source

MiR-124-3p attenuates hyperphosphorylation of tau protein-induced apoptosis via caveolin-1-PI3K/Akt/GSK3β pathway in N2a/APP695swe cells

open access: yesOncoTarget, 2017
Hyperphosphorylation of Tau forming neurofibrillary tangles has been considered as a crucial event in the pathogenesis of Alzheimer's disease (AD). MiR-124-3p belongs to microRNA (miRNA) family and was markedly decreased in AD, however, the functions of ...
Qingmei Kang   +11 more
semanticscholar   +1 more source

Differences in stability and calcium sensitivity of the Ig domains in titin's N2A region

open access: yesProtein Science, 2020
Titin is a large filamentous protein that spans half a sarcomere, from Z‐disk to M‐line. The N2A region within the titin molecule exists between the proximal immunoglobulin (Ig) region and the PEVK region and protein–protein interactions involving this ...
Colleen M. Kelly   +3 more
semanticscholar   +1 more source

Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells

open access: yesFrontiers in Neuroscience, 2017
Recent studies have demonstrated that formaldehyde (FA)—induced neurotoxicity is important in the pathogenesis of Alzheimer's disease (AD). Elevated levels of FA have been associated with memory impairments and the main hallmarks of AD pathology ...
Xiaping He   +9 more
semanticscholar   +1 more source

Third International Meeting of ISEV 2014: Rotterdam, The Netherlands, April 30th – May 3rd, 2014

open access: yes, 2014
Journal of Extracellular Vesicles, Volume 3, Issue 1, January 2014.
wiley   +1 more source

Royal jelly peptides: potential inhibitors of β-secretase in N2a/APP695swe cells

open access: yesScientific Reports, 2019
Royal jelly (RJ) is a type of natural health product with a long history of use. Royal jelly peptides (RJPs) obtained from RJ have numerous bioactivities.
Xueqing Zhang   +5 more
semanticscholar   +1 more source

Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells

open access: yesAging, 2019
The accumulation of autophagosomes and dysfunction at the axonal terminal of neurons play crucial roles in the genesis and development of Alzheimer’s disease (AD). Abnormalities in neuron axonal transport-related proteins prevent autophagosome maturation
Jie Liang   +7 more
semanticscholar   +1 more source

Malathion increases apoptotic cell death by inducing lysosomal membrane permeabilization in N2a neuroblastoma cells: a model for neurodegeneration in Alzheimer’s disease

open access: yesCell Death Discovery, 2017
Malathion is an organophosphate with severe neurotoxic effects. Upon acute exposure, malathion initially enhances cholinergic activity by inhibition of acetylcholinesterase, which is its major pathological mechanism.
Ramu Venkatesan   +4 more
semanticscholar   +1 more source

Octadecaneuropeptide (ODN) Induces N2a Cells Differentiation through a PKA/PLC/PKC/MEK/ERK-Dependent Pathway: Incidence on Peroxisome, Mitochondria, and Lipid Profiles

open access: yesMolecules, 2019
Neurodegenerative diseases are characterized by oxidative stress, mitochondrial damage, and death of neuronal cells. To counteract such damage and to favor neurogenesis, neurotrophic factors could be used as therapeutic agents. Octadecaneuropeptide (ODN),
Amira Namsi   +10 more
semanticscholar   +1 more source

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