Results 1 to 10 of about 34,725 (50)

A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

Basic & Clinical Pharmacology & Toxicology, 2022
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis extracts which has high affinity on a series of receptors, including Type 1 cannabinoid receptor (CB1), Type 2 cannabinoid receptor (CB2), GPR55, transient receptor potential ...
Jiangling Peng, Mingjie Fan, Chelsea An, Feng Ni, Wendong Huang, Jiankang Luo   +5 more
semanticscholar   +1 more source

Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US.

Journal of the American Medical Association (JAMA), 2023
This study assesses the actual measured quantities of melatonin and cannabidiol (CBD) in products marketed and sold in the US as melatonin gummies compared with the quantities declared on their labels.
Pieter A. Cohen, B. Avula, Yan-Hong Wang, Kumar Katragunta, I. Khan   +4 more
semanticscholar   +1 more source

Emerging Therapeutic Potential of Cannabidiol (CBD) in Neurological Disorders: A Comprehensive Review

Behavioural Neurology, 2023
Cannabidiol (CBD), derived from Cannabis sativa, has gained remarkable attention for its potential therapeutic applications. This thorough analysis explores the increasing significance of CBD in treating neurological conditions including epilepsy ...
Kuldeep Singh, Bharat Bhushan, D. Chanchal, Satish Kumar Sharma, Ketki Rani, Manoj Kumar Yadav, Prateek Porwal, Shivendra Kumar, Ashwani Sharma, Tarun Virmani, G. Kumar, Abdullah Al Noman   +11 more
semanticscholar   +1 more source

THC and CBD: Villain versus Hero? Insights into Adolescent Exposure

International Journal of Molecular Sciences, 2023
Cannabis is the most used drug of abuse worldwide. It is well established that the most abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD).
Nicholas Pintori, Francesca Caria, M. A. De Luca, C. Miliano   +3 more
semanticscholar   +1 more source

Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)

Chemical Research in Toxicology, 2023
Cannabis-based products have experienced notable increases in co-usage alongside tobacco products. Several cannabinoids exhibit inhibition of a number of cytochrome P450 (CYP) and UDP glucuronosyltransferase (UGT) enzymes, but few studies have examined ...
Shamema Nasrin, Shelby M. Coates, Keti Bardhi, C. Watson, J. Muscat, P. Lazarus   +5 more
semanticscholar   +1 more source

Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios

Neuropsychopharmacology, 2022
As countries adopt more permissive cannabis policies, it is increasingly important to identify strategies that can reduce the harmful effects of cannabis use.
Amir Englund, D. Oliver, E. Chesney, Lucy Chester, Jack Wilson, Simina Sovi, A. De Micheli, J. Hodsoll, P. Fusar-Poli, J. Strang, Robin M. Murray, T. Freeman, P. McGuire   +12 more
semanticscholar   +1 more source

Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review

Biology, 2022
Simple Summary Emerging evidence suggests positive outcomes from the use of CBD as a cancer treatment. CBD can relieve cancer pain and ease the side effects of chemotherapy; however, there is less research about the mechanism of CBD’s anticancer effects.
Camren G. Heider, Sasha A. Itenberg, Jiajia Rao, Hang Ma, Xian-jie Wu   +4 more
semanticscholar   +1 more source

Cannabidiol (CBD) in Cancer Management

Cancers, 2022
Simple Summary Cannabidiol (CBD) is one of the main constituents of the plant Cannabis sativa. Surveys suggest that medicinal cannabis is popular amongst people diagnosed with cancer.
K. O’Brien
semanticscholar   +1 more source

A new Cannabis genome assembly associates elevated cannabidiol (CBD) with hemp introgressed into marijuana

New Phytologist, 2021
Summary Demand for cannabidiol (CBD), the predominant cannabinoid in hemp (Cannabis sativa), has favored cultivars producing unprecedented quantities of CBD.
Christopher J. Grassa, G. Weiblen, Jonathan P Wenger, Clemon J. Dabney, Shane G. Poplawski, S. T. Motley, T. Michael, C. Schwartz   +7 more
semanticscholar   +1 more source

Impact of Harvest Time and Pruning Technique on Total CBD Concentration and Yield of Medicinal Cannabis

Plants, 2022
The definition of optimum harvest and pruning interventions are important factors varying inflorescence yield and cannabinoid composition. This study investigated the impact of (i) harvest time (HT) and (ii) pruning techniques (PT) on plant biomass ...
Danilo Crispim Massuela, Jens Hartung, Sebastian Munz, Federico Erpenbach, S. Graeff‐Hönninger   +4 more
semanticscholar   +1 more source