Results 251 to 260 of about 48,916 (295)

Cannabidiol as a Prophylactic Agent Against Glioblastoma Growth: A Preclinical Investigation. [PDF]

Int J Mol Sci
Wang LP, Bhandari B, Naeini SE, Hill B, Rogers HM, Gouron J, Perez-Morales N, Khan A, Meeks W, El-Marakby A, Young N, Vale FL, Ali S, Wallace G, Yu JC, Arbab AS, Salles ÉL, Baban B.   +17 more
europepmc   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Cannabidiol-Ion Channel Interactions Represent a Promising Preventive and Therapeutic Strategy in Hepatocellular Carcinoma. [PDF]

Pathophysiology
Chávez-López MG, Avalos-Fuentes A, Cruz-Manzo EDC, Aguirre-Arriaga PA, Florán B, Pérez-Carreón JI, Bañuelos C, Camacho J.   +7 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Hemp (<i>Cannabis sativa</i> L.) Phytochemicals and Their Potential in Agrochemical, Cosmetic, and Food Industries: A Review. [PDF]

Int J Mol Sci
Trono D.
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Cannabidiol-Loaded Mucoadhesive PLGA Nanosphere-Chitosan Hydrogel Patch for Oral Therapeutic Applications. [PDF]

Int J Mol Sci
Chuluunbaatar BA, Park J, Song J, Mun S, Kang JH, Min KH.   +5 more
europepmc   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Advances in biliary stone management: Latest-generation extracorporeal shock wave lithotripsy <i>vs</i> laser lithotripsy for difficult bile duct stones. [PDF]

World J Hepatol
Singla N, Venkata KA, Inavolu P, Memon SF, Koduri KK, Singh AP, Katamareddy T, Darisetty S, Koppoju V, Jagtap N, Kalpala R, Lakhtakia S, Ramchandani M, Tandan M, Reddy DN.   +14 more
europepmc   +1 more source

Vapor pressure measurements on Δ⁹-tetrahydrocannabinol, cannabidiol, and cannabinol to inform cannabis breathalyzer development. [PDF]

J Breath Res
Beuning CN, Berry JL, Paulechka E, Huber ML, Jeerage KM, Widegren JA, Lovestead TM.   +6 more
europepmc   +1 more source