Results 21 to 30 of about 34,725 (50)
Cannabidiol (CBD) in Rheumatic Diseases (Musculoskeletal Pain)
Current Rheumatology Reports, 2022 This review will address the many uncertainties surrounding the medical use of cannabidiol (CBD). We will begin with an overview of the legal and commercial environment, examine recent preclinical and clinical evidence on CBD, explore questions ...
K. Boehnke, W. Häuser, M. Fitzcharles
semanticscholar +1 more source
High-CBD Extract (CBD-X) Downregulates Cytokine Storm Systemically and Locally in Inflamed Lungs
Frontiers in Immunology, 2022 Cytokine storm refers to the dysregulated production of inflammatory mediators leading to hyperinflammation. They are often detrimental, and worsen the severity of COVID-19 and other infectious or inflammatory diseases.
M. Aswad +7 more
semanticscholar +1 more source
Addiction, 2020 BACKGROUND AND AIMS Cannabis products with high delta-9-tetrahydrocannabinol (THC) concentrations carry an increased risk of addiction and mental health disorders, while it has been suggested that cannabidiol (CBD) may moderate the effects of THC.
T. Freeman +6 more
semanticscholar +1 more source
CBD in the Treatment of Epilepsy
MoleculesIt has been several years since highly purified cannabidiol (CBD) was registered as a medication that can be used in children of at least 2 years of age to treat different types of seizures related to Lennox–Gastaut syndrome (LGS), Dravet syndrome (DS ...
Kinga K. Borowicz-Reutt +2 more
semanticscholar +1 more source
Towards Better Delivery of Cannabidiol (CBD)
Pharmaceuticals, 2020 Cannabidiol (CBD) has substantial therapeutic potential, but its development as an effective drug by the pharmaceutical industry is hindered by intrinsic characteristics such as low bioavailability, low water solubility, and variable pharmacokinetic ...
S. Millar +3 more
semanticscholar +1 more source
The proposed mechanisms of action of CBD in epilepsy.
Epileptic disorders, 2020 Highly purified cannabidiol (CBD) (approved as Epidiolex® in the United States and as EPIDYOLEX from the EU agency) has demonstrated efficacy with an acceptable safety profile in patients with Lennox-Gastaut or Dravet syndrome in four randomized ...
R. Gray, Benjamin J. Whalley
semanticscholar +1 more source
CBD, a precursor of THC in e-cigarettes
Scientific Reports, 2021 The use of cannabidiol (CBD) in electronic cigarettes is widespread. Previously, it was reported that CBD is partly transformed to THC in case smoking as a cigarette, however, the pyrolysis of this compound has not been assessed extensively.
Z. Czégény +8 more
semanticscholar +1 more source
Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
Clinical, Cosmetic and Investigational Dermatology, 2020 Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is modulated by the human endocannabinoid system (ECS).
S. Baswan +6 more
semanticscholar +1 more source
Cannabis and Cannabinoid Research, 2021 Introduction: Cannabidiol (CBD), cannabinol (CBN), and Δ9-tetrahydrocannabinol (Δ9-THC) are major cannabinoids in cannabis resin and products. The kinetic of the chemical reaction of resin cannabis is important for product development and storage.
W. Jaidee +6 more
semanticscholar +1 more source
The Essential Medicinal Chemistry of Cannabidiol (CBD).
Journal of Medicinal Chemistry, 2020 This Miniperspective of the published essential medicinal chemistry of cannabidiol (CBD) provides evidence that the popularization of CBD-fortified or CBD-labelled health products, and associated health claims, lack a rigorous scientific foundation.
Kathryn M. Nelson +9 more
semanticscholar +1 more source