Results 1 to 10 of about 140,024 (373)

Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles [PDF]

open access: yesStructure, 2015
CBR hydroxamidines are small-molecule inhibitors of bacterial RNA polymerase (RNAP) discovered through high-throughput screening of synthetic-compound libraries. CBR pyrazoles are structurally related RNAP inhibitors discovered through scaffold hopping from CBR hydroxamidines. CBR hydroxamidines and pyrazoles selectively inhibit Gram-negative bacterial
Feng, Yu   +11 more
openaire   +3 more sources

Assessment of strength development in stabilized soil with CBR PLUS and silica sand

open access: diamond, 2017
This paper investigates the potential use of a nano polymer stabilizer, namely CBR PLUS for stabilization of soft clay and formulation of an optimal mix design of stabilized soil with CBR PLUS and silica sand.
Seyed Esmaeil Mousavi   +1 more
openalex   +2 more sources

Prediction of Strength and CBR Characteristics of Chemically Stabilized Coal Gangue: ANN and Random Forest Tree Approach

open access: yesMaterials, 2022
Coal mining waste in the form of coal gangue (CG) was established recently as a potential fill material in earthworks. To ascertain this potential, this study forecasts the strength and California Bearing Ratio (CBR) characteristics of chemically ...
M. Amin   +7 more
semanticscholar   +1 more source

PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib

open access: yesOxidative Medicine and Cellular Longevity, 2022
PHGDH attaches importance to serine biosynthesis in cancer cells and maintaining mitochondrial redox homeostasis. However, the role of PHGDH inhibitor CBR‐5884 in cell ROS level and its downstream pathways has not been explored in epithelial ovarian ...
Xiaocui Zhang   +4 more
semanticscholar   +1 more source

Histopathological and Immunological Findings in the Common Marmoset Following Exposure to Aerosolized SARS-CoV-2

open access: yesViruses, 2022
There is an enduring requirement to develop animal models of COVID-19 to assess the efficacy of vaccines and therapeutics that can be used to treat the disease in humans.
Rachel E. Ireland   +8 more
doaj   +1 more source

SUSCEPTIBILITY OF SYRIAN HAMSTERS TO NIPAH VIRUS INFECTION

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: Nipah virus is an emerging zoonotic pathogen that causes disease outbreaks in South-East Asia with high case fatality rates. It is considered to be a public health risk and there are limited medical countermeasures for treatment or prevention, and
S. Smither   +4 more
doaj   +1 more source

Validity of the Cauchy-Born rule applied to discrete cellular-scale models of biological tissues. [PDF]

open access: yes, 2013
The development of new models of biological tissues that consider cells in a discrete manner is becoming increasingly popular as an alternative to continuum methods based on partial differential equations, although formal relationships between the ...
Byrne, Helen   +4 more
core   +4 more sources

Stabilisation of peat with colloidal nano and micro silica [PDF]

open access: yesMires and Peat, 2022
Peat occurs abundantly in wetlands across Iran, particularly around the disappearing Urmia Lake. Conventional chemical stabilisation has been widely used to tackle the high compressibility and shrinkage potential of peat. Whilst effective, this generally
Soheil Ghadr, Arya Assadi-Langroudi
doaj   +1 more source

Establishment of a Novel Oral Murine Model of Ricin Intoxication and Efficacy Assessment of Ovine Ricin Antitoxins

open access: yesToxins, 2020
Ricin, produced from the castor beans of Ricinus communis, is a cytotoxin that exerts its action by inactivating ribosomes and causing cell death. Accidental (e.g., ingestion of castor beans) and/or intentional (e.g., suicide) exposure to ricin through ...
Sarah J. Whitfield   +6 more
doaj   +1 more source

Aerosol Survival, Disinfection and Formalin Inactivation of Nipah Virus

open access: yesViruses, 2022
Nipah virus is a relatively newly discovered emerging virus on the WHO list of priority pathogens which has the potential to cause outbreaks with high fatality rates.
Sophie J. Smither   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy