Results 151 to 160 of about 2,964,584 (287)

CC 2009 Ata 06

, 2012
Ata da sexta sessão do CC de ...

core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Global, regional, and national burdens of human papillomavirus-associated cervical cancer attributable to sexually acquired human papillomavirus infections among individuals aged 10-54 years from 1990 to 2021: findings from the Global Burden of Disease study 2021. [PDF]

Sex Med
Nov P, Wang D, Tan M, Virak V, Zhou X, Liu K, Zhu Y, Zhou S, Zhu H.   +8 more
europepmc   +1 more source

CC 2010 Convocação 005

, 2012
Convocação da quinta sessão do CC de ...

core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

<i>De novo</i> grafted coiled-coil peptides as p53/<i>h</i>DM2 inhibitors. [PDF]

RSC Chem Biol
Spain F, Gimenez D, Acevedo-Jake AM, Mylemans B, Brooks NJ, Korona B, Huang DT, Edwards TA, Leney AC, Itzhaki L, Woolfson DN, Wilson AJ.   +11 more
europepmc   +1 more source

CC 2011 Ata 01

, 2012
Ata da primeira sessão do CC em ...

core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Scleroderma calcinosis cutis score (SC2S): an imaging metric to quantify SSc-calcinosis cutis. [PDF]

Rheumatology (Oxford)
Odell ID, Cheung C, Wu M, Perez S, Dixit A, van Horn C, Hamdan M, Gunes I, Kujawski S, Lee H, Wang A, Esserman D, Zamani M, Wilson FP, Onofrey J, Papademetris X, Hinchcliff M.   +16 more
europepmc   +1 more source

CC 2010 Convocação 003

, 2012
Convocação da terceira sessão do CC de ...

core