Results 91 to 100 of about 434,277 (273)

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

Machine Learning‐Guided Engineering of Protein Phase Separation Properties in Immune Regulation

Advanced Science, EarlyView.
PScalpel, a machine learning model integrating protein structure extraction, graph contrastive learning, and a genetic algorithm, guides the engineering of protein phase separation ability. It adopts transfer learning methods to provide predictive recommendations for protein phase separation ability changes through single amino acid mutations in a ...
Chenqiu Zhang, Jia Wang, Zhe Wang, Liyan Zhu, Sihui Cai, Luzhi Zhan, Haorui Liang, Yaoxing Wu, Jianqiang Li, Jun Cui   +9 more
wiley   +1 more source

Ní­­veis de energia metabolizável para rações de rã touro

Boletim do Instituto de Pesca, 2018
O objetivo do presente estudo foi avaliar os efeitos da interação entre o ní­­vel de proteí­­na bruta (PB) e de energia metabolizável (EM) na ração de rãs através do desempenho dos animais (ganho de peso, consumo alimentar, conversão alimentar) e do ...
Josevane Carvalho CASTRO, Walter Amaral BARBOZA, Késia Karla Paiva SILVA, Sérgio Ceotto PIRES   +3 more
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Federica Doglio in a dialogue with Mirko Zardini: A book interview on crises during a crisis

Festival dell'Architettura Magazine, 2021
Review of the book   Authors: Federica Doglio, Mirko Zardini Edited by: Federica Doglio Title: Dopo le Crisi Subtitle: 1978, 2001, 2008, 2020 Language: Italiano Publisher: LetteraVentidue Characteristic: Format 10x15cm forma, 128 pages, paperback ...
Claudia Mainardi
doaj  

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

A CLE11b‐CLE16 Signaling Relay Mediates Root‐Shoot‐Root Crosstalk for Drought Adaptation in Common Bean

Advanced Science, EarlyView.
A novel root‐shoot‐root signaling relay, mediated by CLE peptides, coordinates drought adaptation in common bean. Root‐derived PvCLE11b translocates acropetally to leaves, inducing PvCLE16 expression via PvTCP10. Leaf‐accumulated PvCLE16 triggers stomatal closure and translocates basipetally to modulate root architecture.
Xinyang Wu, Shiyuan Tao, Zhuoyi Wang, Ting Sun, Zixin Zhang, Su Yang, Min Xu, Chenyi Huang, Siyi Wang, Xubo Ke, Chenze Lu, Kang Ning, Pei Xu   +12 more
wiley   +1 more source

Economy and Environmental Problems in the Mexican Coastal States [PDF]

A canonical correspondence analysis (CCA) for environmental and economic variables was performed for 17 Mexican coastal states. The ordination method allowed us to identify three groups, namely hydroelectric energy generation (I), pollution (II) and ...
Alfredo Ortega Rubio, Felipe García-Rodríguez, José Borges Contreras, José Urciaga García, Luis F. Beltrán Morales   +4 more
core  

Predicting High‐Resolution Spatial and Spectral Features in Mass Spectrometry Imaging with Machine Learning and Multimodal Data Fusion

Advanced Intelligent Discovery, EarlyView.
A multimodal fusion pipeline predicts high‐resolution ion distributions in imaging mass spectrometry by integrating Fourier transform ion cyclotron resonance, time‐of‐flight matrix‐assisted laser desorption/ionization, and time‐of‐flight secondary ion mass spectrometry data.
Md Inzamam Ul Haque, Ramakrishnan Kannan, Jacob D. Hinkle, Sylwia A. Stopka, Anton V. Ievlev, Nathalie Y. R. Agar, Olga S. Ovchinnikova, Debangshu Mukherjee   +7 more
wiley   +1 more source

Produção de mudas de maracujazeiro amarelo submetidãs à salinidade em solo como biofertilizante bovino

Ciencia del Suelo
O experimento foi desenvolvido em abrigo protegido no período de 1 de maio a 31 de julho de 2008, no município de Areia, estado da Paraíba, PB, Brasil, com objetivo de estudar os efeitos da salinidade da água de irrigação sobre o comportamento inicial de
Francisco De Oliveira Mesquita, Lourival Ferreira Cavalcante, Walter Esfrain Pereira, Alex heus Rebequi, Antonio João De Lima Neto, Járisson Cavalcante Nunes   +5 more
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High Levels of Serum IgG for Opisthorchis viverrini and CD44 Expression Predict Worse Prognosis for Cholangiocarcinoma Patients after Curative Resection

International Journal of General Medicine, 2021
Attapol Titapun,1,2 Vor Luvira,1,2 Tharatip Srisuk,1,2 Apiwat Jareanrat,1,2 Vasin Thanasukarn,1,2 Malinee Thanee,2,3 Prakasit Sa-Ngiamwibool,2,3 Sureerat Padthaisong,2,4 Kassaporn Duangkumpha,2,4 Manida Suksawat,2,4 Watcharin Loilome,2,4 Paiboon ...
Titapun A, Luvira V, Srisuk T, Jareanrat A, Thanasukarn V, Thanee M, Sa-Ngiamwibool P, Padthaisong S, Duangkumpha K, Suksawat M, Loilome W, Sithithaworn P, Techasen A, Thinkhamrop B, Dzienny A, Caglayan A, Park D, Mahmud S, Khuntikeo N   +18 more
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