Results 91 to 100 of about 128,485 (263)

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Introduction of a Double‐Headed Nucleotide Into G‐Quadruplex DNA: Position‐Dependent Stabilization and Structural Insights

Chemistry – A European Journal, EarlyView.
A double‐headed bis‐guanine (G) nucleotide (GG) was evaluated as a noncanonical building block in G‐quadruplexes (G4s). Biophysical and computational analyses reveal that GG can directly participate in G‐tetrads and strongly stabilize G4s in a position‐ and topology‐dependent manner. These findings establish design rules for using GG to engineer highly
Krista Urup, Peter Reinholdt, Kasper Munch Beck, Michael Petersen, Jean‐Louis Mergny, Poul Nielsen   +5 more
wiley   +1 more source

BIOMASSA DO MARACUJAZEIRO-AMARELO EM SOLO IRRIGADO COM ÁGUA SALINA PROTEGIDO CONTRA AS PERDAS HÍDRICAS

Revista Verde de Agroecologia e Desenvolvimento Sustentável, 2008
Foi conduzido um experimento em campo, no período de março/2002 a abril/2003, no município de Remígio – PB, usando blocos casualizados em esquema fatorial 3x2x2, para avaliar os efeitos da condutividade elétrica da água de irrigação: 0,5; 1,5 e 2,5 dS m ...
Lourival Ferreira Cavalcante, Melcior Naelson Batista da Silva, Adriana Araújo Diniz, Ítalo Herberth Lucena Cavalcante, Vinícius Batista Campos   +4 more
doaj  

Aqueous Supercapacitor with Wide‐Temperature Operability and over 100,000 Cycles Enabled by Water‐in‐Salt Electrolyte

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
This study presents a symmetric supercapacitor with activated carbon electrodes and a “water‐in‐salt” electrolyte (WiSE) based on lithium perchlorate, offering over 100,000 cycles with over 90 % capacity retention. The supercapacitor operates efficiently from −20 to 80 °C, enhancing performance, stability, and all‐season operability.
Zahid Ali Zafar, Radim Weisser, Ghulam Abbas, Martin Silhavik, Prabhat Kumar, Jiří Červenka   +5 more
wiley   +1 more source

CytoScan: Automated Detection of Technical Anomalies for Cytometry Quality Control

Cytometry Part A, EarlyView.
ABSTRACT Studies evaluating cellular phenotypes by cytometry techniques are increasingly facing analytical challenges due to the multitudes of samples and parameters that are evaluated concurrently. Spurious technical effects resulting from a lack of standardization can affect marker distributions and further complicate multi‐sample analyses.
Tim R. Mocking, Felix Zwolle, Yejin Park, Angèle Kelder, Yvan Saeys, Jacqueline Cloos, Sofie van Gassen, Costa Bachas   +7 more
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Substratos na produção de porta-enxertos cítricos em ambiente protegido

Revista Verde de Agroecologia e Desenvolvimento Sustentável, 2012
Um fator a ser considerado na citricultura é a produção de mudas de qualidade, utilizandosubstratos de boa qualidade física, química e biológica. No mercado, existem poucas marcas de substratos para a cultura dos citros, o que encarece o preço final da ...
Leandro Firmino Fernandes, Wiara Assis Gomes, Rejane Maria Nunes Mendonça   +2 more
doaj  

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Evaluation the physiological quality of Brachiaria brizantha cv. BRS 'Piatã' seeds

Bioscience Journal, 2017
In a quality control program, seed vigor evaluation is of fundamental importance for the success of the program. The objective of this project was to evaluate the efficiency of several vigor tests to evaluate the physiological quality of Brachiaria ...
Givanildo Zildo da Silva, Cibele Chalita Martins, José de Oliveira Cruz, Tatiane Sanches Jeromini, Riselane de Lucena Alcântara Bruno   +4 more
doaj  

An accessible microfluidic perfusion platform for time‐restricted control of zebrafish embryonic patterning

Developmental Dynamics, EarlyView.
Abstract Understanding the dynamic nature of developmental networks requires live imaging techniques capable of capturing real‐time developmental processes in wild‐type and mutant embryos as they are exposed to pharmacological perturbations. A peculiar developmental patterning process in early vertebrate embryos is the sequential segmentation of ...
Mohammed Nakhuda, M. Fethullah Simsek
wiley   +1 more source