Results 21 to 30 of about 125,234 (245)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Fertilizer consumption survey and use of soil analysis by small and medium farmers in Araras-SP area, Brazil

Revista Ciência em Extensão, 2009
The use of fertilizers and soil amendments is an important factor which leads to increase agricultural productivity. However, the inadequate use of these inputs has been causing economical, agronomic, and environmental impacts in the activities of small ...
Marcio Roberto Soares, José Carlos Casagrande, Joice Natália Sossai, Edson Pereira da Mota, José Renato Donadon, Luiz Hamilton de Moura Montans Neto, Bruno Milan, Fábio Fabrini Cruger, Rafael José Pereira Rovêa, João Pedro Alves dos Santos   +9 more
doaj  

Época de semeadura de aveia branca (Avena sativa L.) para produção de grãos no Estado de Santa Catarina

Agropecuária Catarinense, 2022
O presente trabalho teve como objetivo estudar épocas de semeadura para a cultura da aveia, visando a produção com alto rendimento e qualidade de grãos.
Antonio Carlos Alves, Levi Ribas de Miranda Ramos   +1 more
doaj  

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Contribuição ao estudo da qualidade do leite

Agropecuária Catarinense, 2022
O objetivo deste trabalho é testar a eficiência da pasteurização lenta, instalada num condomínio leiteiro rural, comparando-a com um sistema de pasteurização rápida, normalmente utilizado em usinas de pasteurização.
Juliana Maria Amábile, Honório Domingos Benedet   +1 more
doaj  

Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites

Advanced Functional Materials, EarlyView.
A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu, Yuqi Zhang, Alysse DeFoe, Georgios Kotsaris, Brendan Stoeckl, Matthew D. Davidson, Jason A. Burdick, Robert L. Mauck   +7 more
wiley   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

ACÚMULO DE BIOMASSA PELA MAMONEIRA SUBMETIDA A DIFERENTES ADUBAÇÕES E APLICAÇÃO DE ESCÓRIA DE SIDERURGIA

Revista Verde de Agroecologia e Desenvolvimento Sustentável, 2010
A mamoneira (Ricinus communis L.) é uma planta exigente em nutrientes e sensível a acidez do solo, apresentando boa resposta em produtividade à correção do solo e à adubação. Este trabalho buscou avaliar o efeito de diferentes adubações (mineral, esterco
Wagner Nunes Rodrigues, Henrique Otes Nicoline, Lima Deleon Martins, Marcelo Antonio Tomaz, José Francisco Teixeira do Amaral   +4 more
doaj  

Photochromic Cholesteric Liquid Crystals via Arylazopyrazole Functionalization of Hydroxypropyl Cellulose

Advanced Materials, EarlyView.
We produce a new derivative of hydroxypropyl cellulose functionalized with arylazopyrazole side chains and demonstrate its photoswitchable behaviors in dilute and concentrated aqueous solutions, ultimately designing a series of photochromic cholesteric materials that can be photopatterned as write‐erase displays.
Simona G. Fine, Nina Hildenhagen, Walter R. Linke, Michael Ryan Hansen, Bart Jan Ravoo, Cécile A. C. Chazot   +5 more
wiley   +1 more source