Results 171 to 180 of about 3,609 (205)
Adhirons are efficient tools to guide antiviral ligand discovery. [PDF]
Commun BiolFlynn AJ +5 more
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Cross-Neutralization of Hazara Virus by Convalescent Sera from CCHFV- Infected Individuals
Bakangil Ö., Doymaz M. Z.
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Neutralizing Potential of CCHFV Sera from Multiple Species Against Hazara Virus Infection
Bakangil Ö., Doymaz M. Z.
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Emerging Microbes and InfectionsThe Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne bunyavirus that causes high mortality in humans. This enveloped virus harbors two surface glycoproteins (GP), Gn and Gc, that are released by processing of a glycoprotein precursor complex whose maturation takes place in the ER and is completed through the secretion pathway.
Anupriya Gautam +2 more
exaly +6 more sources
Fluorometric CCHFV OTU protease assay with potent inhibitors
Virus Genes, 2015 Crimean-Congo hemorrhagic fever virus (CCHFV) is a deadly virus that has been listed in the Category C as a potential bioterror agent. There are no specific therapies against CCHFV, which urges identification of potential therapeutic targets and development of CCHFV therapies.
Fatih Kocabas +2 more
exaly +4 more sources
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Favipiravir and Ribavirin protect immunocompetent mice from lethal CCHFV infection
Antiviral Research, 2023Crimean-Congo hemorrhagic fever virus (CCHFV) causes Crimean-Congo hemorrhagic fever (CCHF) in humans with high morbidity and mortality. Currently, there is neither an approved antiviral drug nor a vaccine against CCHFV. In this study, we describe a lethal model of CCHFV infection using a mouse-adapted strain of CCHFV (MA-CCHFV) in adult wild-type male
Thomas Tipih +7 more
openaire +2 more sources
Virologica Sinica, 2010 The Crimean-congo hemorrhagic fever virus (CCHFV) is a geographically widespread fatal pathogen. Identification of the epitope regions of the virus is important for the diagnosis and epidemiological studies of CCHFV infections. In this study, expression vectors carrying series truncated fragments of the NP (nucleocapsid protein) gene from the S ...
Hua-Lin Wang, Zhihong Hu, Fei Deng
exaly +4 more sources
Tropical Animal Health and Production, 2012
In this study, the hard ticks, whole blood and serum samples collected from small ruminants (sheep and goat) in middle Black Sea region of Turkey where Crimean-Congo hemorrhagic fever (CCHF) human cases were observed in the past years were surveyed for the presence of RNA and specific IgG antibodies from CCFH virus (CCHFV). CCHFV RNA was found in 30 of
Harun Albayrak +2 more
exaly +4 more sources
In this study, the hard ticks, whole blood and serum samples collected from small ruminants (sheep and goat) in middle Black Sea region of Turkey where Crimean-Congo hemorrhagic fever (CCHF) human cases were observed in the past years were surveyed for the presence of RNA and specific IgG antibodies from CCFH virus (CCHFV). CCHFV RNA was found in 30 of
Harun Albayrak +2 more
exaly +4 more sources
Experimental Challenge of Sheep and Cattle with Dugbe Orthonairovirus, a Neglected African Arbovirus Distantly Related to CCHFV [PDF]
Viruses, 2021 Dugbe orthonairovirus (DUGV) is a tick-borne arbovirus within the order Bunyavirales. DUGV was first isolated in Nigeria, but virus isolations in ten further African countries indicate that DUGV is widespread throughout Africa. Humans can suffer from a mild febrile illness, hence, DUGV is classified as a biosafety level (BSL) 3 agent.
Christine Fast +2 more
exaly +5 more sources