Results 1 to 10 of about 13,353 (200)

Host Community Traits Driving Crimean-Congo Hemorrhagic Fever Virus Maintenance in Iberian Ecosystems. [PDF]

Transbound Emerg Dis
Crimean‐Congo hemorrhagic fever (CCHF) is a tick‐borne zoonosis of significant public health concern, maintained in complex multihost systems shaped by ecological, climatic, and anthropogenic drivers. In the Iberian Peninsula, changing land‐use patterns and biodiversity loss may be reshaping host communities in ways that alter local transmission ...
Xavier P, Perelló A, Luque-Castro V, Relimpio D, Barroso P, Almeida V, de la Fuente J, Balseiro A, Ruiz-Fons F, Gortázar C.   +9 more
europepmc   +2 more sources

Development and Characterization of Microsatellite Genetic Markers for <i>Hyalomma rufipes</i>, a Tick Vector of Crimean-Congo Hemorrhagic Fever Virus. [PDF]

Ecol Evol
This study developed and validated 14 polymorphic microsatellite markers to investigate the population genetics of Hyalomma rufipes, a tick species that transmits Crimean‐Congo Hemorrhagic Fever Virus (CCHFV) in East Africa. Ticks collected from livestock in northern Kenya were morphologically and genetically identified, followed by genome sequencing ...
Ahmad H, Aool W, Anyango V, Nakayaki TM, Mulwa F, Chelangat B, Lutwama JJ, Kayondo JK, Lukindu M, Mutisya J, Lutomiah J, Hensley LE, Cohnstaedt LW, Onyango MG, Brelsfoard CL.   +14 more
europepmc   +2 more sources

Crimean-Congo Hemorrhagic Fever Virus in Cattle and Ticks, Israel [PDF]

Emerging Infectious Diseases
We conducted a nationwide serologic and molecular survey to elucidate the epidemiologic status of Crimean-Congo hemorrhagic fever virus in Israel. We found serologic and molecular evidence of virus circulation in the country. Future human cases could be
Nir Rudoler, Marisol Rubinstein-Guini, Asael Roth, Victoria Indenbaum, Oran Erster, Yaniv Lustig, Elad Eliahoo   +6 more
doaj   +2 more sources

Crimean-Congo Hemorrhagic Fever Virus Africa 1 Lineage in Hyalomma dromedarii Ticks, Algeria, 2023. [PDF]

Emerg Infect Dis
We conducted a Crimean-Congo hemorrhagic fever virus (CCHFV) survey of Hyalomma spp. ticks collected from camels in southeastern Algeria. Of 138 tick pools, 1 was CCHFV positive; the sequenced strain belonged to the Africa 1 genotype.
Temani M, Hachid A, Garni R, Guessoum AA, Benaissa MH, Khardine AF, Kimouche A, Hakem A, Bitam I, Benallal KE, Lafri I.   +10 more
europepmc   +2 more sources

Crimean-Congo Hemorrhagic Fever Virus Circulation in Wild European Rabbits, Portugal, 2018−2023 [PDF]

Emerging Infectious Diseases
Crimean-Congo hemorrhagic fever virus is considered a public health risk in southwestern Europe. We surveyed serum samples from 667 European rabbits across Portugal, a rabbit species known to host immature Hyalomma lusitanicum ticks. We found low levels
Carolina Baptista, Nuno Santos, Laurence Vial, Ferran Jori   +3 more
doaj   +2 more sources

Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread. [PDF]

Sci Transl Med
Crimean-Congo hemorrhagic fever virus (CCHFV) is a priority pathogen transmitted by tick bites, with no vaccines or specific therapeutics approved to date. Severe disease manifestations include hemorrhage, endothelial dysfunction, and multiorgan failure.
Pahmeier F, Monticelli SR, Feng X, Hjorth CK, Wang A, Kuehne AI, Bakken RR, Batchelor TG, Lee SE, Middlecamp M, Stuart L, Duarte-Neto AN, Abelson DM, McLellan JS, Biering SB, Herbert AS, Chandran K, Harris E.   +17 more
europepmc   +2 more sources

Crimean Congo Hemorrhagic Fever Virus for Clinicians-Virology, Pathogenesis, and Pathology. [PDF]

Emerg Infect Dis
Crimean-Congo hemorrhagic fever (CCHF), caused by CCHF virus, is a tickborne disease that can cause a range of illness outcomes, from asymptomatic infection to fatal viral hemorrhagic fever; the disease has been described in >30 countries. We conducted a
Frank MG, Weaver G, Raabe V, State of the Clinical Science Working Group of the National Emerging Pathogens Training and Education Center’s Special Pathogens Research Network.   +3 more
europepmc   +2 more sources

Replicating RNA vaccination elicits an unexpected immune response that efficiently protects mice against lethal Crimean-Congo hemorrhagic fever virus challenge

EBioMedicine, 2022
Summary: Background: Crimean-Congo hemorrhagic fever virus is the cause of a severe hemorrhagic fever with cases reported throughout a wide-geographic region.
Shanna S. Leventhal, Kimberly Meade-White, Deepashri Rao, Elaine Haddock, Jacqueline Leung, Dana Scott, Jacob Archer, Samantha Randall, Jesse H. Erasmus, Heinz Feldmann, David W. Hawman   +10 more
doaj   +2 more sources

Crimean-Congo Hemorrhagic Fever Virus for Clinicians-Epidemiology, Clinical Manifestations, and Prevention. [PDF]

Emerg Infect Dis
Crimean-Congo hemorrhagic fever (CCHF) is a tickborne infection that can range from asymptomatic to fatal and has been described in >30 countries. Early identification and isolation of patients with suspected or confirmed CCHF and the use of appropriate ...
Frank MG, Weaver G, Raabe V, State of the Clinical Science Working Group of the National Emerging Pathogens Training, Education Center’s Special Pathogens Research Network2, State of the Clinical Science Working Group of the National Emerging Pathogens Training Education Center’s Special Pathogens Research Network.   +5 more
europepmc   +2 more sources

Engineering and structures of Crimean-Congo hemorrhagic fever virus glycoprotein complexes. [PDF]

Cell
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tickborne virus that can cause severe disease in humans with case fatality rates of 10%-40%. Although structures of CCHFV glycoproteins GP38 and Gc have provided insights into viral entry and defined ...
McFadden E, Monticelli SR, Wang A, Ramamohan AR, Batchelor TG, Kuehne AI, Bakken RR, Tse AL, Chandran K, Herbert AS, McLellan JS.   +10 more
europepmc   +2 more sources