Results 21 to 30 of about 10,763 (250)

Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread. [PDF]

Sci Transl Med
Crimean-Congo hemorrhagic fever virus (CCHFV) is a priority pathogen transmitted by tick bites, with no vaccines or specific therapeutics approved to date. Severe disease manifestations include hemorrhage, endothelial dysfunction, and multiorgan failure.
Pahmeier F, Monticelli SR, Feng X, Hjorth CK, Wang A, Kuehne AI, Bakken RR, Batchelor TG, Lee SE, Middlecamp M, Stuart L, Duarte-Neto AN, Abelson DM, McLellan JS, Biering SB, Herbert AS, Chandran K, Harris E.   +17 more
europepmc   +2 more sources

Crimean Congo Hemorrhagic Fever Virus for Clinicians-Virology, Pathogenesis, and Pathology. [PDF]

Emerg Infect Dis
Crimean-Congo hemorrhagic fever (CCHF), caused by CCHF virus, is a tickborne disease that can cause a range of illness outcomes, from asymptomatic infection to fatal viral hemorrhagic fever; the disease has been described in >30 countries. We conducted a
Frank MG, Weaver G, Raabe V, State of the Clinical Science Working Group of the National Emerging Pathogens Training and Education Center’s Special Pathogens Research Network.   +3 more
europepmc   +2 more sources

Immunocompetent mouse model for Crimean-Congo hemorrhagic fever virus

eLife, 2021
Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne febrile illness with wide geographic distribution. CCHF is caused by infection with the Crimean-Congo hemorrhagic fever virus (CCHFV) and case fatality rates can be as high as 30%.
David W Hawman, Kimberly Meade-White, Shanna Leventhal, Friederike Feldmann, Atsushi Okumura, Brian Smith, Dana Scott, Heinz Feldmann   +7 more
doaj   +3 more sources

Engineering and structures of Crimean-Congo hemorrhagic fever virus glycoprotein complexes. [PDF]

Cell
SUMMARY Crimean–Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus that can cause severe disease in humans with case fatality rates of 10–40%.
McFadden E, Monticelli SR, Wang A, Ramamohan AR, Batchelor TG, Kuehne AI, Bakken RR, Tse AL, Chandran K, Herbert AS, McLellan JS.   +10 more
europepmc   +2 more sources

Phylogenetic Characterization of Crimean-Congo Hemorrhagic Fever Virus, Spain [PDF]

Emerging Infectious Diseases, 2017
Two cases of Crimean-Congo hemorrhagic fever were reported in Spain during 2016. We obtained the virus from a patient sample and characterized its full genomic sequence.
Eva Ramírez de Arellano, Lourdes Hernández, M. José Goyanes, Marta Arsuaga, Ana Fernández Cruz, Anabel Negredo, María Paz Sánchez-Seco   +6 more
doaj   +5 more sources

Crimean–Congo Hemorrhagic Fever Virus: Progress in Vaccine Development

Diagnostics, 2023
Crimean–Congo hemorrhagic fever virus (CCHFV), a member of the Nairoviridae family and Bunyavirales order, is transmitted to humans via tick bites or contact with the blood of infected animals.
A. Ozdarendeli
semanticscholar   +5 more sources

Host genetic diversity contributes to disease outcome in Crimean-Congo hemorrhagic fever virus infection [PDF]

npj Viruses
The Crimean-Congo hemorrhagic fever virus (CCHFV) causes Crimean-Congo hemorrhagic fever (CCHF), a widely distributed disease with significant morbidity and mortality.
Deepashri Rao, Matthew Lewis, Kimberly Meade-White, Carl Shaia, Atsushi Okumura, Martin T. Ferris, Alexandra Schäfer, Ralph Baric, Heinz Feldmann, David W. Hawman   +9 more
doaj   +2 more sources

Subclinical Infections with Crimean-Congo Hemorrhagic Fever Virus, Turkey

Emerging Infectious Diseases, 2012
To investigate Crimean-Congo hemorrhagic fever virus in Turkey, we conducted a seroepidemiologic survey during January–April 2009. Seroprevalence of infection was 10% in a sample from an outbreak region and increased with patient age, indicating that the
Hürrem Bodur, Esragül Akinci, Sibel Ascioglu, Pinar Öngürü, Yavuz Uyar   +4 more
doaj   +5 more sources

Recent advances in understanding Crimean–Congo hemorrhagic fever virus [PDF]

F1000Research, 2018
Crimean-Congo hemorrhagic fever virus (CCHFV) is a widely distributed hemorrhagic fever virus and the cause of hemorrhagic disease in Africa, Southern and Eastern Europe, the Middle East, India and Asia.
David W. Hawman, H. Feldmann
semanticscholar   +3 more sources

Crimean-Congo Hemorrhagic Fever Virus, Northeastern Greece

Emerging Infectious Diseases, 2011
To the Editor: Crimean-Congo hemorrhagic fever virus (CCHFV) causes a disease in humans that is characterized by fever and hemorrhagic manifestations, with death rates up to 30%. Humans are infected through tick bites or contact with the viremic blood of patients or livestock.
Anna Papa, Evangelia Tzala, Helena C. Maltezou   +2 more
doaj   +3 more sources