Results 11 to 20 of about 13,422 (244)

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus [PDF]

Viruses, 2016
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen that causes high morbidity and mortality. Efficacy of vaccines and antivirals to treat human CCHFV infections remains limited and controversial. Research into pathology and underlying
M. Zivcec, F. Scholte, C. Spiropoulou, J. Spengler, É. Bergeron   +4 more
semanticscholar   +6 more sources

Crimean-Congo Hemorrhagic Fever Virus, Greece

Emerging Infectious Diseases, 2014
Seroprevalence of Crimean-Congo hemorrhagic fever virus (CCHFV) is high in some regions of Greece, but only 1 case of disease has been reported. We used 4 methods to test 118 serum samples that were positive for CCHFV IgG by commercial ELISA and ...
Anna Papa, Persefoni Sidira, Victor Larichev, Ludmila Gavrilova, Ksenia Kuzmina, Mehrdad Mousavi-Jazi, Ali Mirazimi, Ute Ströher, Stuart Nichol   +8 more
doaj   +3 more sources

Crimean-Congo Hemorrhagic Fever Virus: Current Advances and Future Prospects of Antiviral Strategies

Viruses, 2021
Crimean-Congo hemorrhagic fever virus (CCHFV) is a widespread, tick-borne pathogen that causes Crimean-Congo hemorrhagic fever (CCHF) with high morbidity and mortality.
Shiyu Dai, Fei Deng, Hualin Wang, Yunjia Ning   +3 more
doaj   +3 more sources

Phylogeography of Crimean Congo Hemorrhagic Fever Virus.

PLoS ONE, 2016
Crimean Congo hemorrhagic fever virus (CCHFV) is one of the most severe viral zoonozes. It is prevalent throughout Africa, Asia and southern Europe. Limited availability of sequence data has hindered phylogeographic studies. The complete genomic sequence
Alexander N Lukashev, Alexander S Klimentov, Svetlana E Smirnova, Tamara K Dzagurova, Jan Felix Drexler, Anatoly P Gmyl   +5 more
doaj   +6 more sources

Crimean-Congo Hemorrhagic Fever Virus in Asia, Africa and Europe [PDF]

Microorganisms, 2021
The global spread of ticks and various tick-borne viruses (TBVs) suggests the possibility of new tick-borne diseases emerging. Crimean-Congo hemorrhagic fever virus (CCHFV) is an emerging TBV of the Nairoviridae family that causes serious disease that ...
N. Shahhosseini, Gary Wong, G. Babuadze, Jeremy V. Camp, O. Ergonul, G. Kobinger, S. Chinikar, N. Nowotny   +7 more
semanticscholar   +5 more sources

Immunocompetent mouse model for Crimean-Congo hemorrhagic fever virus

eLife, 2021
Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne febrile illness with wide geographic distribution. CCHF is caused by infection with the Crimean-Congo hemorrhagic fever virus (CCHFV) and case fatality rates can be as high as 30%.
David W Hawman, Kimberly Meade-White, Shanna Leventhal, Friederike Feldmann, Atsushi Okumura, Brian Smith, Dana Scott, Heinz Feldmann   +7 more
doaj   +3 more sources

Host genetic diversity contributes to disease outcome in Crimean-Congo hemorrhagic fever virus infection [PDF]

npj Viruses
The Crimean-Congo hemorrhagic fever virus (CCHFV) causes Crimean-Congo hemorrhagic fever (CCHF), a widely distributed disease with significant morbidity and mortality.
Deepashri Rao, Matthew Lewis, Kimberly Meade-White, Carl Shaia, Atsushi Okumura, Martin T. Ferris, Alexandra Schäfer, Ralph Baric, Heinz Feldmann, David W. Hawman   +9 more
doaj   +2 more sources

Crimean–Congo Hemorrhagic Fever Virus: Progress in Vaccine Development

Diagnostics, 2023
Crimean–Congo hemorrhagic fever virus (CCHFV), a member of the Nairoviridae family and Bunyavirales order, is transmitted to humans via tick bites or contact with the blood of infected animals.
A. Ozdarendeli
semanticscholar   +5 more sources

Recent advances in understanding Crimean–Congo hemorrhagic fever virus [PDF]

F1000Research, 2018
Crimean-Congo hemorrhagic fever virus (CCHFV) is a widely distributed hemorrhagic fever virus and the cause of hemorrhagic disease in Africa, Southern and Eastern Europe, the Middle East, India and Asia.
David W. Hawman, H. Feldmann
semanticscholar   +3 more sources

Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease.

Cell Reports, 2017
Antiviral responses are regulated by conjugation of ubiquitin (Ub) and interferon-stimulated gene 15 (ISG15) to proteins. Certain classes of viruses encode Ub- or ISG15-specific proteases belonging to the ovarian tumor (OTU) superfamily.
F. Scholte, M. Zivcec, J. V. Dzimianski, Michelle K. Deaton, J. Spengler, S. R. Welch, S. Nichol, S. Pegan, C. Spiropoulou, É. Bergeron   +9 more
semanticscholar   +3 more sources