Results 11 to 20 of about 10,763 (250)

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus [PDF]

Viruses, 2016
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen that causes high morbidity and mortality. Efficacy of vaccines and antivirals to treat human CCHFV infections remains limited and controversial. Research into pathology and underlying
Marko Zivcec, Florine E M Scholte, Christina F Spiropoulou   +2 more
exaly   +5 more sources

Replicating RNA vaccination elicits an unexpected immune response that efficiently protects mice against lethal Crimean-Congo hemorrhagic fever virus challenge

EBioMedicine, 2022
Summary: Background: Crimean-Congo hemorrhagic fever virus is the cause of a severe hemorrhagic fever with cases reported throughout a wide-geographic region.
Shanna S. Leventhal, Kimberly Meade-White, Deepashri Rao, Elaine Haddock, Jacqueline Leung, Dana Scott, Jacob Archer, Samantha Randall, Jesse H. Erasmus, Heinz Feldmann, David W. Hawman   +10 more
doaj   +4 more sources

Crimean-Congo Hemorrhagic Fever Virus in Cattle and Ticks, Israel [PDF]

Emerging Infectious Diseases
We conducted a nationwide serologic and molecular survey to elucidate the epidemiologic status of Crimean-Congo hemorrhagic fever virus in Israel. We found serologic and molecular evidence of virus circulation in the country. Future human cases could be
Nir Rudoler, Marisol Rubinstein-Guini, Asael Roth, Victoria Indenbaum, Oran Erster, Yaniv Lustig, Elad Eliahoo   +6 more
doaj   +4 more sources

Crimean-Congo Hemorrhagic Fever Virus, Greece

Emerging Infectious Diseases, 2014
Seroprevalence of Crimean-Congo hemorrhagic fever virus (CCHFV) is high in some regions of Greece, but only 1 case of disease has been reported. We used 4 methods to test 118 serum samples that were positive for CCHFV IgG by commercial ELISA and ...
Anna Papa, Persefoni Sidira, Victor Larichev, Ludmila Gavrilova, Ksenia Kuzmina, Mehrdad Mousavi-Jazi, Ali Mirazimi, Ute Ströher, Stuart Nichol   +8 more
doaj   +3 more sources

Crimean-Congo Hemorrhagic Fever Virus: Current Advances and Future Prospects of Antiviral Strategies

Viruses, 2021
Crimean-Congo hemorrhagic fever virus (CCHFV) is a widespread, tick-borne pathogen that causes Crimean-Congo hemorrhagic fever (CCHF) with high morbidity and mortality.
Shiyu Dai, Fei Deng, Hualin Wang, Yunjia Ning   +3 more
doaj   +3 more sources

Crimean-Congo Hemorrhagic Fever Virus in Asia, Africa and Europe [PDF]

Microorganisms, 2021
The global spread of ticks and various tick-borne viruses (TBVs) suggests the possibility of new tick-borne diseases emerging. Crimean-Congo hemorrhagic fever virus (CCHFV) is an emerging TBV of the Nairoviridae family that causes serious disease that ...
N. Shahhosseini, Gary Wong, G. Babuadze, Jeremy V. Camp, O. Ergonul, G. Kobinger, S. Chinikar, N. Nowotny   +7 more
semanticscholar   +5 more sources

Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease

Cell Reports, 2017
SUMMARY Antiviral responses are regulated by conjugation of ubiquitin (Ub) and interferon-stimulated gene 15 (ISG15) to proteins. Certain classes of viruses encode Ub- or ISG15-specific proteases belonging to the ovarian tumor (OTU) superfamily.
Florine E M Scholte, Marko Zivcec, John V Dzimianski   +2 more
exaly   +2 more sources

GP38 as a vaccine target for Crimean-Congo hemorrhagic fever virus

npj Vaccines, 2023
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic disease in humans. There is a great need for effective vaccines and therapeutics against CCHFV for humans, as none are currently internationally approved ...
Gabrielle Scher, D. Bente, Megan C. Mears, M. Cajimat, M. Schnell   +4 more
semanticscholar   +4 more sources

Crimean-Congo Hemorrhagic Fever Virus Circulation in Wild European Rabbits, Portugal, 2018−2023 [PDF]

Emerging Infectious Diseases
Crimean-Congo hemorrhagic fever virus is considered a public health risk in southwestern Europe. We surveyed serum samples from 667 European rabbits across Portugal, a rabbit species known to host immature Hyalomma lusitanicum ticks. We found low levels
Carolina Baptista, Nuno Santos, Laurence Vial, Ferran Jori   +3 more
doaj   +2 more sources

Crimean-Congo Hemorrhagic Fever Virus Africa 1 Lineage in Hyalomma dromedarii Ticks, Algeria, 2023. [PDF]

Emerg Infect Dis
We conducted a Crimean-Congo hemorrhagic fever virus (CCHFV) survey of Hyalomma spp. ticks collected from camels in southeastern Algeria. Of 138 tick pools, 1 was CCHFV positive; the sequenced strain belonged to the Africa 1 genotype.
Temani M, Hachid A, Garni R, Guessoum AA, Benaissa MH, Khardine AF, Kimouche A, Hakem A, Bitam I, Benallal KE, Lafri I.   +10 more
europepmc   +2 more sources