Results 61 to 70 of about 29,920 (249)

Cerebral Cavernous Malformation: From Genetics to Pharmacotherapy

Brain and Behavior
Introduction Cerebral cavernous malformation (CCM) is a type of cerebrovascular abnormality in the central nervous system linked to both germline and somatic genetic mutations.
Zhuangzhuang Zhang, Jianwen Deng, Weiping Sun, Zhaoxia Wang   +3 more
doaj   +1 more source

Association of the nicotinic receptor α7 subunit gene (CHRNA7) with schizophrenia and visual backward masking

Frontiers in Psychiatry, 2013
The nicotinic system is involved in the pathophysiology of schizophrenia. However, very little is known about its genetic basis and how it relates to clinical symptoms and potentially pharmacological intervention.
George eBakanidze, Maya eRoinishvili, Eka eChkonia, Werner eKitzrow, Sarina eRichter, Konrad eNeumann, Michael eHerzog, Andreas eBrand, Imke ePuls   +8 more
doaj   +1 more source

Prior Outpatient Care Use in Emergency Department Patients with Low- and High-acuity Conditions in Germany

Western Journal of Emergency Medicine
Introduction: The key role of emergency departments (ED) is to treat severe and life-threatening cases. A rise in ED visits, particularly for low-acuity conditions, places a burden on resources which may hinder efficient care for high-acuity conditions ...
Yves N. Wu, Martin Möckel, Dörte Huscher, Antje Fischer-Rosinský, Thomas Keil, Anna Slagman   +5 more
doaj   +1 more source

Two‐Dimensional Flow and Thermal Energy Transfer in Non‐Newtonian Casson–Carreau Ternary Hybrid Nanofluids Over Stationary and Moving Wedge Surfaces With Radiation and Magnetic Field Effects

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Efficient thermal management in advanced industrial systems requires improved heat transfer performance, particularly under non‐Newtonian fluid behavior and complex surface geometries. This study investigates the two‐dimensional flow and heat transfer characteristics of ternary hybrid nanofluids over both stationary and moving wedge surfaces ...
A. O. Akindele, A. M. Obalalu, M. O. Afolabi, Umair Khan, Samia Elattar   +4 more
wiley   +1 more source

Neuroanatomical diversity in Teleocichla with new volumetric and histological insights into the encephalon of Teleocichla monogramma Kullander 1988

The Anatomical Record, EarlyView.
Abstract Teleocichla comprises small cichlids that inhabit the rapid streams of Amazonian rivers; however, there has been limited research on their encephalon morphology. This study examined the neuroanatomy of four species, focusing on volumetric measurements of their encephalon subregions, and providing a histological description of the encephalon of
Renan Leão‐Reis, Keila Xavier Magalhães, Thiago Nilton A. Pereira, Janice Muriel‐Cunha, Alberto Akama   +4 more
wiley   +1 more source

The performance of ChatGPT and other large language models on multiple‐choice questions in biomedical disciplines: A meta‐analysis

Anatomical Sciences Education, EarlyView.
Abstract While large language models (LLMs) have shown promise as learning tools for medical education, their reported accuracy on multiple‐choice questions (MCQs) varies widely across studies, necessitating synthesis. This meta‐analysis synthesizes LLM accuracy on text‐based MCQs from biomedical disciplines and USMLE Step 1‐level content and explores ...
Colleen M. Cheverko, Volodymyr Mavrych, Olena Bolgova, Fathima Raahima Riyas Mohamed, Jennifer Westrick, Lorena Juarez, Emily Rush, Kathryn A. Solka, Alison F. Doubleday, Jessica N. Byram, Robert Becker, Victoria Gomez, Brenda K. Anak Ganeng, Leslie A. Hoffman, Victoria A. Roach, Kirsten M. Brown, Nicole DeVaul, Colleen N. Garnett, Hannah L. Herriott, Rebecca S. Lufler, Jason C. Mussell, Joy Y. Balta, Michael A. Pascoe, Jason W. Middleton, Sharon Duffy, Georgina C. Stephens, Adam B. Wilson   +26 more
wiley   +1 more source

Illicium verum Essential Oil Antimicrobial Activity in vitro and in situ

Scientific Papers Animal Science and Biotechnologies, 2023
Star anise, or Illicium verum, is a widely used term. Star anise, a culinary flavor that is primarily used in Asian nations, is derived from the evergreen Chinese plant Illicium verum.
Natália Čmiková, Simona Kunová, Miroslava Kačániová   +2 more
doaj  

Hair analysis of formoterol as a novel tool to assess long‐term inhalation medication adherence: Data from the TRICOLON trial

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this paper is to examine inhaled formoterol concentrations in hair and assess the potential of hair analysis as a tool for measuring long‐term adherence, by validation with objective data from digital inhalers. Methods Hair samples and digital inhaler data were collected from patients with COPD in 10 hospitals in the Netherlands as part ...
Liz J. A. Cuperus, A. Mireille A. Wessels, Huib A. M. Kerstjens, Daan J. Touw, Erik W. M. A. Bischoff, Job van der Palen, Arnoud Aldenkamp, Astrid van Huisstede, Folkert Brijker, Stephan Dik, Lidwien Graat‐Verboom, Martijn Goosens, Peter Th. W. van Hal, Jolanda C. Kuijvenhoven, Lisette I. Z. Kunz, Renske van der Meer, Mariette H. A. Scholma‐Bronsema, Job F. M. van Boven, Johannes C. C. M. in't Veen, the TRICOLON study group, Marjo van der Poel, Irini Piso, Marijke Amelink, Anke Rol, Jennifer de Graaf, Petra Hirmann, Fleur van Tour, Elly Jordens, Lydia Alfing, Gerda Lenderink, Truus Rietveld, Jasmijn van Campen, Jantine de Bruijn, Janice van ter Burg, Liselore Baarssmit, Walter van Litsenburg, Len Knoops, Margot Eggermont‐Schilt, Manon de Waard‐Heijligers, Ilonka Paalvast‐Schouten, Mariette Scholma, Sandra Brookman‐Mozes, Inge Paas, Lidwien Verboom, Karin van Mierlo‐Snoeijs   +44 more
wiley   +1 more source

Sustained pharmacodynamic effects of S‐ketamine on cortical excitability and resting‐state brain activity: A randomized, placebo‐controlled trial

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate a set of pharmacodynamic biomarkers reflecting acute, delayed and sustained central nervous system effects of S‐ketamine, used as a tool compound for rapid‐acting antidepressant activity, with the goal of informing biomarker strategies for delayed antidepressant effects.
Catherine M. K. E. de Cuba, Annika A. de Goede, Joost. C. van Mechelen, Laura G. J. M. Borghans, Liam van der Aa, Erik Olofsen, Maria J. Juachon, Robert J. Doll, Amy Gillespie, Catherine J. Harmer, Gabriël E. Jacobs, Jules A. A. C. Heuberger   +11 more
wiley   +1 more source

Homologous tumor‐targeting biomimetic nanozyme for synergistic NIR‐II photothermal and chemodynamic therapy

BMEMat, EarlyView.
Studies reveal that a biomimetic nanoplatform based on a cancer cell membrane‐camouflaged Au‐MnOx nanozyme (Au‐MnOx@CCM) can achieve synergistic antitumor therapy by combining NIR‐II mediated PTT with enhanced CDT, offering a promising strategy for precise and efficient tumor therapy. Abstract The therapeutic potential of nanozyme‐mediated chemodynamic
Xiaonan Li, Siman Luo, Yucheng Zuo, Liheng Chen, Houjuan Zhu, Jing‐Yi Zhu, Wei Xue   +6 more
wiley   +1 more source