Inflammatory Mechanisms in a Neurovascular Disease: Cerebral Cavernous Malformation [PDF]
Brain Sciences, 2023 Cerebral cavernous malformation (CCM) is a common cerebrovascular malformation causing intracranial hemorrhage, seizures, and focal neurologic deficits.
Ying Li +9 more
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Cranial ultrasonography in diagnosis of infantile cerebral cavernous malformation [PDF]
Clinical Case Reports, 2023 The case of an infantile cerebral cavernous malformation detected by transfontanelle cranial ultrasonography. Infantile cerebral cavernous malformations tend to cause more major bleeding compared to those in older groups, so early detection and treatment
Shuya Kaneko, Iku Ikeno, Hideo Wada
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Signalling through cerebral cavernous malformation protein networks [PDF]
Open Biology, 2020 Cerebral cavernous malformations (CCMs) are neurovascular abnormalities characterized by thin, leaky blood vessels resulting in lesions that predispose to haemorrhages, stroke, epilepsy and focal neurological deficits.
Valerie L. Su, David A. Calderwood
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Cerebral Cavernous Malformation: From Genetics to Pharmacotherapy [PDF]
Brain and BehaviorIntroduction Cerebral cavernous malformation (CCM) is a type of cerebrovascular abnormality in the central nervous system linked to both germline and somatic genetic mutations.
Zhuangzhuang Zhang +3 more
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A Spinal Cavernous Malformation in Multiple Cerebral Cavernous Venous Malformations Syndrome
Journal of the Belgian Society of Radiology, 2023 Teaching Point: In patients with familial multiple cavernous malformation syndrome with acute focal neurological deficit, a symptomatic spinal cavernous malformation must be included in the differential diagnosis.
Guillaume Vangrinsven +2 more
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Functional outcome after pediatric cerebral cavernous malformation surgery [PDF]
Scientific Reports, 2023 The purpose of this study was to investigate the functional outcome following surgical resection of cerebral cavernous malformations (CCM) in pediatric patients.
Laurèl Rauschenbach +11 more
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The Role of Immune Infiltration and Oxidative Stress in the Progression of Cerebral Cavernous Malformation [PDF]
Brain and BehaviorPurpose of Review To review how the immune microenvironment and oxidative stress modulate the initiation, maturation, and hemorrhagic conversion of cerebral cavernous malformations (CCM) and to appraise the therapeutic potential of immune‐directed ...
Xuesai Zhu +3 more
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Anticoagulant Use during Subacute Asymptomatic Cerebral Cavernous Malformation Hemorrhage [PDF]
Case Reports in NeurologyIntroduction: Several cohort analyses and 2 meta-analyses show a lower risk of cerebral cavernous malformation (CCM) hemorrhage in patients taking anti-thrombotics than those without.
Kelly Flemming +2 more
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MEKK3 bridges gut-brain communication and cerebral cavernous malformation pathogenesis [PDF]
Cell Death DiscoveryCerebral cavernous malformation (CCM) is a condition affecting the brain vasculature, characterized by endothelial dysfunction and abnormal vascular structure. In recent years, the gut-brain axis has emerged as a significant regulatory factor influencing
Peng Cheng +8 more
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Case Report: A novel heterozygous nonsense mutation in KRIT1 cause hereditary cerebral cavernous malformation [PDF]
Frontiers in Oncology, 2023 Cerebral cavernous malformation (CCM) is a vascular malformation of the central nervous system and mainly characterized by enlarged capillary cavities without intervening brain parenchyma. Genetic studies have identified three disease-causing genes (CCM1/
Zhenxing Liu +3 more
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