Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman
Cerebral cavernous malformations (CCMs) are dilated blood vessels which can develop sporadically or in familial form and are the commonest malformations of blood vessels in the spinal cord and brain.
Klenam Dzefi-Tettey +4 more
doaj +2 more sources
A Spinal Cavernous Malformation in Multiple Cerebral Cavernous Venous Malformations Syndrome
Teaching Point: In patients with familial multiple cavernous malformation syndrome with acute focal neurological deficit, a symptomatic spinal cavernous malformation must be included in the differential diagnosis.
Guillaume Vangrinsven +2 more
openaire +6 more sources
SURGERY FOR CAVERNOUS MALFORMATION OF THE CEREBRAL TRUNK [PDF]
We present a surgical case with a patient treated for multiple cerebral cavernomas, manifesting with trunk extravasations. This case has special feature as the patient’s twin-sister had asymptomatic cavernous malformation.
V. V. Tkachev +3 more
doaj +3 more sources
The Role of Intraoperative Neurophysiological Monitoring in Intracranial Cavernous Malformation Surgery: A Narrative Review [PDF]
Cavernous malformations, also known as cavernous hemangiomas or cavernomas, are abnormal vascular lesions that can occur in various parts of the body, including intracranially.
Mei Shao +6 more
doaj +3 more sources
A Systematic Review of Cerebral Arteriovenous Malformation Management
Cerebral Arteriovenous Malformation is a neurovascular lesion characterized by an abnormal connection between arterial and venous systems, resulting in a tangle of blood vessels lacking intervening capillaries.
Karen Eliahu +2 more
doaj +3 more sources
Cavernous malformation hemorrhage due to trans-mural pressure alterations after cerebrospinal fluid diversion: a case report [PDF]
Background Cavernous malformations are rare cerebral pseudo-vascular lesions with annualized bleeding rates of 0.5–3% in most studies. Of the various explored risk factors for bleeding to date, only prior hemorrhage has shown significant correlation ...
Benjamin R. Hartley +2 more
doaj +2 more sources
The Emerging Role of the Gut Microbiome in Cerebral Cavernous Malformation: A New Novel Therapeutic Strategy? [PDF]
Cerebral cavernous malformation (CCM) is a cluster of abnormal blood vessels in the brain that leads to severe neurological deficits, seizures, and fatal hemorrhagic stroke. Currently, there is no available drug treatment for CCM.
Sadegh H, Choi JP.
europepmc +2 more sources
Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation [PDF]
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Zheng W +17 more
europepmc +2 more sources
Cranial ultrasonography in diagnosis of infantile cerebral cavernous malformation
The case of an infantile cerebral cavernous malformation detected by transfontanelle cranial ultrasonography. Infantile cerebral cavernous malformations tend to cause more major bleeding compared to those in older groups, so early detection and treatment
Shuya Kaneko, Iku Ikeno, Hideo Wada
doaj +1 more source
Cerebral cavernous malformations and epilepsy [PDF]
✓Seizures and epilepsy are frequent clinical manifestations of cerebral cavernous malformations (CCMs) and represent the most common symptomatic presentation of supratentorial lesions. Clinicians often diagnose CCMs in patients after a first seizure, or in some cases after obtaining neuroimaging studies in patients suffering from chronic epilepsy ...
Issam, Awad, Pascal, Jabbour
openaire +2 more sources

