Results 31 to 40 of about 8,444 (208)

The cerebral cavernous malformations proteins

Oncotarget, 2015
Inherited mutations in three genes lead to the familial form of Cerebral Cavernous Malformations (CCM). These vascular dysplasias most commonly occur in the brain, and manifest as dilated, mulberry-shaped lesions with a single endothelial layer. The consequences of these lesions can be leakage and sequelae such as focal neurological deficits, epilepsy,
Xiaofeng, Li, Oriana S, Fisher, Titus J, Boggon   +2 more
openaire   +2 more sources

Variable expression of cerebral cavernous malformations in carriers of a premature termination codon in exon 17 of the Krit1 gene [PDF]

, 2003
Background Cerebral cavernous malformations (CCM) present as either sporadic or autosomal dominant conditions with incomplete penetrance of symptoms. Differences in genetic and environmental factors might be minimized among first-degree relatives.
Miguel Lucas, Alzenire F Costa, José M García-Moreno, Francisca Solano, Miguel A Gamero, Guillermo Izquierdo, P Labauge, S Laberge-le Couteulx, T Sahoo, M Lucas, DJ Verlaan, M Lucas, I Serebriiskii, J Zhang, T Sahoo, J Zhang, JS Zawistowski, HH Jung, HD Craig   +18 more
core   +3 more sources

Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman

Case Reports in Radiology, 2021
Cerebral cavernous malformations (CCMs) are dilated blood vessels which can develop sporadically or in familial form and are the commonest malformations of blood vessels in the spinal cord and brain.
Klenam Dzefi-Tettey, Emmanuel Kobina Mesi Edzie, Philip Narteh Gorleku, Henry Kusodzi, Abdul Raman Asemah   +4 more
doaj   +1 more source

Stereotactic Radiosurgery for Management of Cavernous Malformations [PDF]

, 2015
Cavernous malformations (CMs) are abnormal vascular formations of the brain with an estimated incidence of 0.4%-0.8% in the general population.1 CMs have the potential to cause significant morbidity, and have been associated with epileptic seizures ...
Chalouhi, MD, Nohra, Jabbour, Pascal, MD, Nasca, BA, BS, Brian, Rosenwasser MD, Robert H., Tjoumakaris, Stavropoula, Viereck, Matthew J   +5 more
core   +2 more sources

Intraoperative MRI-assisted neuro-port surgery for the resection of cerebral intraparenchymal cavernous malformation

Chinese Neurosurgical Journal, 2019
Background Intraparenchymal cerebral cavernous malformation is difficult to localize intraoperatively with conventional frameless navigation due to the “brain shift” effect.
Min Zhao, Changyu Lu, Jianfeng Liang, Yuanli Zhao, Xiaolei Chen   +4 more
doaj   +1 more source

Cavernous malformation hemorrhage due to trans-mural pressure alterations after cerebrospinal fluid diversion: a case report

BMC Neurology, 2020
Background Cavernous malformations are rare cerebral pseudo-vascular lesions with annualized bleeding rates of 0.5–3% in most studies. Of the various explored risk factors for bleeding to date, only prior hemorrhage has shown significant correlation ...
Benjamin R. Hartley, Corinne Birnbaum, Caitlin E. Hoffman   +2 more
doaj   +1 more source

Contralateral Anterior Interhemispheric–Transcallosal–Transrostral Approach for the Resection of a Subcallosal Cavernous Malformation: A Case Report and an Operative Video

Frontiers in Surgery, 2022
This case report demonstrates the surgical resection of a cerebral cavernous malformation located in the subcallosal region. The authors present a detailed operative video explaining the steps to successfully remove the lesion through a contralateral ...
Aderaldo Costa Alves, Marco Antônio Zanini, Pedro Tadao Hamamoto Filho, Feres Eduardo Aparecido Chaddad-Neto   +3 more
doaj   +1 more source

The Role of Intraoperative Neurophysiological Monitoring in Intracranial Cavernous Malformation Surgery: A Narrative Review [PDF]

Iranian Journal of Medical Sciences
Cavernous malformations, also known as cavernous hemangiomas or cavernomas, are abnormal vascular lesions that can occur in various parts of the body, including intracranially.
Mei Shao, Qi-Yang Huai, Jian-Wei Song, Fu-Qiang Wang, Yan-Na Li, Xia Li, Feng-Ling Wang   +6 more
doaj   +1 more source

A novel CCM2 variant in a family with non-progressive cognitive complaints and cerebral microbleeds [PDF]

, 2017
Lobar cerebral microbleeds are most often sporadic and associated with Alzheimer's disease. The aim of our study was to identify the underlying genetic defect in a family with cognitive complaints and multiple lobar microbleeds and a positive family ...
Barkhof, F. (Frederik), Cohn-Hokke, P.E. (P.), Flier, W.M. (Wiesje) van der, Holstege, H. (Henne), Meijers-Heijboer, E.J. (Hanne), Pijnenburg, Y.A.L. (Yolande), Scheltens, P. (Philip), Sistermans, E.A. (Erik), Swieten, J.C. (John) van, Weiss, M.M. (Marjan M.)   +9 more
core   +1 more source

High-Flow Vascular Malformations in Children. [PDF]

, 2020
Children can have a variety of intracranial vascular anomalies ranging from small and incidental with no clinical consequences to complex lesions that can cause substantial neurologic deficits, heart failure, or profoundly affect development. In contrast
Abla, Adib A, Braunstein, Steve, Cooke, Daniel L, Fullerton, Heather J, Gupta, Nalin, Hetts, Steven W, Kim, Helen, Morshed, Ramin A, Winkler, Ethan A   +8 more
core