Results 21 to 30 of about 613,500 (197)

Vertigo due to cerebellar cavernous malformation: A case report

Radiology Case Reports, 2022
Central vertigo is a result of vestibular structure dysfunction in the central nervous system. Currently, misdiagnoses between peripheral and central lesions are frequent, and diagnostic testing costs are high.
Putri Maharani, MD, Hanik Badriyah Hidayati, MD; PhD, Shahdevi Nandar Kurniawan, MD; PhD   +2 more
doaj   +1 more source

Case Report: A novel heterozygous nonsense mutation in KRIT1 cause hereditary cerebral cavernous malformation

Frontiers in Oncology, 2023
Cerebral cavernous malformation (CCM) is a vascular malformation of the central nervous system and mainly characterized by enlarged capillary cavities without intervening brain parenchyma. Genetic studies have identified three disease-causing genes (CCM1/
Zhenxing Liu, Kaikai Guo, Xuebin Hu, Xianqin Zhang   +3 more
doaj   +1 more source

A novel mutation in KDR is associated with retinal venous beading and cerebral cavernous malformation [PDF]

Genes and Diseases
Xiaonan Zhuang, Yuqiao Ju, Gezhi Xu, Xin Huang   +3 more
doaj   +2 more sources

Generation of an induced pluripotent stem cell line (UNCCi002-A) from a healthy donor using a non-integration system to study Cerebral Cavernous Malformation (CCM)

Stem Cell Research, 2021
The generation of induced pluripotent stem cells (iPSCs) from healthy individuals is an invaluable resource as reference control in disease modeling and drug discovery.
Alvaro A. Beltran, Sarahi G. Molina, Ariana Marquez, Lorena J. Munoz, Jose F. Olivares, Adriana S. Beltran   +5 more
doaj   +1 more source

Rare asymptomatic giant cerebral cavernous malformation in adults: two case reports and a literature review

Journal of International Medical Research, 2020
Cavernous malformations are benign vascular malformations. Giant cavernous malformations are very rare. All reported cases have been symptomatic because of the large size and compression of the surrounding brain tissue.
Zhen Wang, Junwen Hu, Chun Wang
doaj   +1 more source

Pharmacological blocking of neutrophil extracellular traps attenuates immunothrombosis and neuroinflammation in cerebral cavernous malformation. [PDF]

Nat Cardiovasc Res
Cerebral cavernous malformation (CCM) is a neurovascular disease with symptoms such as strokes, hemorrhages and neurological deficits. With surgery being the only treatment strategy, understanding the molecular mechanisms of CCM is crucial in finding ...
Onyeogaziri FC, Smith R, Arce M, Huang H, Erzar I, Rorsman C, Malinverno M, Orsenigo F, Sundell V, Fernando D, Daniel G, Niemelä M, Laakso A, Jahromi BR, Olsson AK, Magnusson PU.   +15 more
europepmc   +4 more sources

Medical monitoring of patient with cavernous hemangioma of the retina and intracranial involvement

American Journal of Ophthalmology Case Reports, 2020
Purpose: To describe a case report of Cavernous Hemangioma of the Retina (CHR) and highlight the importance of investigating intracranial system when retinal vascular alterations are present.
Laís Yumi Sakano, Carlos Roberto Neufeld, Teruo Aihara   +2 more
doaj   +1 more source

Multiple cerebral cavernous malformations in a pediatric patient with Turner syndrome

Interdisciplinary Neurosurgery, 2017
Turner syndrome (TS; 45,X0) is a relatively common chromosomal disorder that is associated with characteristic phenotypic stigmata: short stature, webbed neck, broad (“shield”) chest with widely spaced nipples, cubitus valgus, ovarian dysgenesis (“streak
Nicholas T. Gamboa, B.S., Elizabeth Carlson, B.S., Min S. Park, M.D., John R. Kestle, M.D., M. Yashar S. Kalani, M.D., Ph.D.   +4 more
doaj   +1 more source

The cerebral cavernous malformations proteins

Oncotarget, 2015
Inherited mutations in three genes lead to the familial form of Cerebral Cavernous Malformations (CCM). These vascular dysplasias most commonly occur in the brain, and manifest as dilated, mulberry-shaped lesions with a single endothelial layer. The consequences of these lesions can be leakage and sequelae such as focal neurological deficits, epilepsy,
Xiaofeng, Li, Oriana S, Fisher, Titus J, Boggon   +2 more
openaire   +2 more sources

sj-pdf-1-jcb-10.1177_0271678X221105995 - Supplemental material for Cerebral cavernous malformation development in chronic mouse models driven by dual recombinases induced gene deletion in brain endothelial cells

, 2022
Supplemental material, sj-pdf-1-jcb-10.1177_0271678X221105995 for Cerebral cavernous malformation development in chronic mouse models driven by dual recombinases induced gene deletion in brain endothelial cells by Xi Yang, Zifeng Dai, Caixia Gao ...
Zhiming Han (151601), Xiangjian Zheng (2938044), Bin Zhou (84959), Caixia Gao (575550), Yue Huang (285485), Zifeng Dai (12861170), Yongqiang Yin (12861173), Changbin Shi (415896), Renjing Liu (153771), Qichuan Zhuge (690521), Xi Yang (112884)   +10 more
core   +1 more source