Results 221 to 230 of about 4,207 (232)

Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease

Developmental Biology, 2012
Neil C Chi, Ian C Scott
exaly  

A novel CCM1/KRIT1 heterozygous deletion mutation (c.1919delT) in a Chinese family with familial cerebral cavernous malformation

Clinical neurology and neurosurgery (Dutch-Flemish ed. Print), 2018
Chenlong Yang, Bing-quan Wu, H. Zhong, Yan Li, Xingzheng Zheng, Yulun Xu   +5 more
semanticscholar   +1 more source

Loss of p53 Sensitizes Mice with a Mutation in Ccm1 (KRIT1) to Development of Cerebral Vascular Malformations

American Journal of Pathology, 2004
Sudha Srinivasan, Douglas A Marchuk
exaly  

High-throughput sequencing of the entire genomic regions of CCM1/KRIT1, CCM2 and CCM3/PDCD10 to search for pathogenic deep-intronic splice mutations in cerebral cavernous malformations.

European Journal of Medical Genetics, 2017
M. Rath, Sönke E Jenssen, Konrad Schwefel, Stefanie Spiegler, Dana Kleimeier, C. Sperling, L. Kaderali, U. Felbor   +7 more
semanticscholar   +1 more source

Identification of a Novel Deletion Mutation (c.1780delG) and a Novel Splice-Site Mutation (c.1412-1G>A) in the CCM1/KRIT1 Gene Associated with Familial Cerebral Cavernous Malformation in the Chinese Population

Journal of Molecular Neuroscience, 2016
Chenlong Yang, Ji-zong Zhao, Bing-quan Wu, H. Zhong, Yan Li, Yulun Xu   +5 more
semanticscholar   +1 more source

CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-β, Wnt and STAT3 signaling pathways

Journal of Food and Drug Analysis, 2019
Yi-Shiou Chiou, Chiung-Tong Chen, Ssu-Ching Chen   +2 more
exaly  

KRIT1/CCM1 Loss-of-function Mutations Impair Anti-glycative and Anti-oxidant Systems Worsening High Fructose Diet-induced Hepatic Dismetabolism

Free Radical Biology & Medicine, 2019

semanticscholar   +1 more source

CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-κB pathways

Scientific Reports, 2017
Min-Hsiung Pan, Chiung-Tong Chen, Chien-Lung Chen   +2 more
exaly  

Exome capture sequencing identifies a novel CCM1 mutation in a Chinese family with multiple cerebral cavernous malformations

International Journal of Neuroscience, 2016
Chengyuan Mao, Jing Yang, Shu-yu Zhang, Hai-yang Luo, B. Song, Yu-tao Liu, Jun Wu, Shilei Sun, Zhihua Yang, Pan Du, Yao-he Wang, Changhe Shi, Yu-ming Xu   +12 more
semanticscholar   +1 more source

A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells

Human Molecular Genetics, 2009
exaly