Species-specific roles of cellular communication network proteins in cartilage development: A comparative study using in vitro chondrogenic models. [PDF]
Cross‐species network analysis identifies CCN1/2 as conserved hubs linking extracellular matrix assembly, growth factor signaling, and mechanosensitive pathways during chondrogenesis, guiding model selection and informing CCN‐targeted cartilage regeneration strategies.
Wang Z +9 more
europepmc +2 more sources
The Role of the Cellular Communication Network Protein Family in Pulmonary Arterial Hypertension. [PDF]
ABSTRACT Pulmonary arterial hypertension (PAH) is a complex progressive disease associated with high morbidity and mortality. Circulating serum biomarkers have the potential to optimize diagnosis and prognosis in PAH. The cellular communication network (CCN) protein family is a group of similarly structured matricellular proteins with many roles ...
Byrd CE +8 more
europepmc +2 more sources
Celebrating milestones in cell communication and signaling: Forthcoming joint ICCNS-ARBIOCOM anniversary meeting. [PDF]
Abstract The Joint Meeting commemorating the 25th anniversary of the International CCN Society (ICCNS) and the 5th anniversary of the Association for Research on Biosignaling and Communication (ARBIOCOM) will take place on December 13–17, 2025, in Nice, France.
Chaqour B, Perbal A, Perbal B.
europepmc +2 more sources
Apoptosis signal-regulating kinase 1 is involved in WISP-1-promoted cell motility in human oral squamous cell carcinoma cells. [PDF]
Oral squamous cell carcinoma (OSCC) has a tendency to migrate and metastasize. WNT1-inducible signaling pathway protein 1 (WISP-1) is a cysteine-rich protein that belongs to the Cyr61, CTGF, Nov (CCN) family of matrix cellular proteins.
Jing-Yuan Chuang +4 more
doaj +1 more source
WISP-3 promotes tumor-monocyte adhesion through a MEK/ERK-dependent miR-12131/ICAM-4 axis in lung adenocarcinoma. [PDF]
Chao CC +6 more
europepmc +1 more source
Nanoparticle-enabled tuning of cell density for enhanced adhesion and tissue repair. [PDF]
Park HS +12 more
europepmc +1 more source
WISP-3 promotes PDGF-B-mediated angiogenesis through suppression of let-7b-5p in rheumatoid arthritis. [PDF]
Wang GS +6 more
europepmc +1 more source
Role of extracellular matrix in liver fibrosis regression and regeneration (Review). [PDF]
Zhou Y +4 more
europepmc +1 more source
Cyr61 Promotes Oral Squamous Cell Carcinoma Cell Motility via an Integrin αvβ3/αvβ5-PLC/PKC/c-Src-AP-1-ICAM-1 Signaling Axis. [PDF]
Lin KC +6 more
europepmc +1 more source
Matricellular Proteins in Bladder Cancer: Context-Dependent Roles in Tumor Promotion and Suppression. [PDF]
Akhmetkaliyev A +3 more
europepmc +1 more source

