Results 181 to 190 of about 262,387 (304)

Real‐world management of adjuvant systemic melanoma therapy: Multi‐center survey of 51 DeCOG skin cancer centers

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Adjuvant immune checkpoint inhibitors (ICI) and targeted therapy (TT) have revolutionized treatment management for patients with melanoma. However, the current German S3 guideline does not differentiate between patients with and without adjuvant therapy in its recommendations for imaging intervals and follow‐up monitoring, leading to
Markus Reitmajer   +11 more
wiley   +1 more source

What's the worth of a promise? Evaluating the long‐term effects of a programme to reduce early marriage in India

open access: yesEconomica, EarlyView.
Abstract This paper examines the long‐term effects of ‘Apni Beti Apna Dhan’ (ABAD), a unique conditional cash transfer programme implemented in the north Indian state of Haryana from 1994 to 1998. The programme provided bonds to female beneficiaries at birth, redeemable on attaining 18 years of age, if they remained unmarried. In particular, we examine
Shreya Biswas, Upasak Das
wiley   +1 more source

Assessment of corneal biomechanical properties using Corvis ST following LASIK, PRK, and CXL. [PDF]

open access: yesLasers Med Sci
Saif PS   +4 more
europepmc   +1 more source

Placebo zones in discontinuity‐based designs: Estimation, inference, and implementation

open access: yesEconomic Inquiry, EarlyView.
Abstract We propose a new model‐selection algorithm for regression discontinuity design and related estimators. The performance of candidate models is assessed within a “placebo zone” of the running variable. Candidate models can differ by bandwidth and other choice parameters.
Nathan Kettlewell, Peter Siminski
wiley   +1 more source

Photoperiod‐Regulated Thermal Tolerance of the Non‐Diapausing Insect Ceratitis capitata (Diptera: Tephritidae)

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
Developmental photoperiodic exposure (photoacclimation) from egg to adult emergence alters thermal tolerance in Ceratitis capitata. Flies reared under contrasting photoperiods (0:24, 8:16, 14:10, and 24:0 L:D) showed significant shifts in both CTmin and CTmax, whereas adult‐only photoacclimation affected CTmax but not CTmin.
Antonis G. Papadopoulos   +1 more
wiley   +1 more source

Automodification of N‐terminal serine residues facilitates PARP2 release from DNA

open access: yesThe FEBS Journal, EarlyView.
PARP2 is involved in detecting DNA damage and its N‐terminal role is largely unknown. Based on biochemical and biophysical data, our findings suggest that in the presence of HPF1, N‐terminal serine 8 and 73 are enriched in auto‐ADP‐ribosylation. Our results provide insight into the mechanistic role of PARP2 N‐terminus in the PARylation‐dependent ...
Saurabh Singh Dhakar   +6 more
wiley   +1 more source

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