The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
The FEBS Journal, EarlyView.Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
Comparison of corneal biomechanics after SMILE versus LASEK in moderate to high myopia with relatively thin corneas: a retrospective comparative study. [PDF]
BMC OphthalmolZhang R +7 more
europepmc +1 more source
A Systematic Review Evaluating Methods for Diagnosis, Treatment and Prevention of Dental Erosions
International Journal of Dental Hygiene, EarlyView.ABSTRACT Aim The aim of this systematic review was to investigate the quality of evidence for methods used to diagnose, restore and prevent dental erosions, by evaluating and summarising clinical controlled studies and in situ studies covering this field.
Maria Skalsky Jarkander +5 more
wiley +1 more source
The Effect of Chlorhexidine Mouthwash on Blood Pressure: A Systematic Review and Meta‐Analysis
International Journal of Dental Hygiene, EarlyView.ABSTRACT Aim This study evaluated the effect of rinsing with a chlorhexidine containing mouthwash (CHX‐MW) on blood pressure (BP), as compared to rinsing with a control MW or no MW, based on (randomised) controlled trials and observational studies in humans. PROSPERO CRD42020222495.
Lars S. J. Toonen +5 more
wiley +1 more source
Cigarette Smoking as an Independent Predictor of Endothelial Cell Loss After Cataract Surgery: A Prospective Cohort Study. [PDF]
Clin OphthalmolConfalonieri F +9 more
europepmc +1 more source
Exploring Toothbrushing Duration Among Adults: A Systematic Review
International Journal of Dental Hygiene, EarlyView.ABSTRACT Aim There is a need for greater understanding of the average brushing time among individuals. Since the average brushing time remains unclear, this study involves a systematic review to assess this aspect of oral hygiene practices and how it has evolved over the years. Material and Methods The PubMed‐MEDLINE and Cochrane‐CENTRAL databases were
Tim M. J. A. Thomassen +3 more
wiley +1 more source
Comparative efficacy of non-pharmacological interventions for post-stroke cognitive impairment: a systematic review and network meta-analysis of randomized controlled trials. [PDF]
Front NeurolNiu H +6 more
europepmc +1 more source
Deep Caries Management: EFCD‐ESE‐ORCA S3‐Level Clinical Practice Guideline
International Endodontic Journal, EarlyView.ABSTRACT Objective To develop an evidence‐based S3‐level clinical practice guideline for the management of deep and extremely deep caries in vital permanent teeth. Methods An evidence‐based medical guideline based on systematically searched and appraised evidence as well as a structured consensus (S3‐level) was jointly developed by the European ...
Falk Schwendicke +11 more
wiley +1 more source
CognIFied: protocol for a pilot randomised controlled trial of a culturally adapted, task-shifted compensatory cognitive training intervention for young adults with first-episode psychosis in Nigeria. [PDF]
BMJ OpenAdewuya AO +6 more
europepmc +1 more source