Results 61 to 70 of about 262,387 (304)

Replacing CCT with “best value” [PDF]

, 1999
Professor Christopher Bovis (University of Central Lancashire) assesses the concept of best value in delivering public services, following the demise of the compulsory competitive tendering (CCT) regime. He compares it with its predecessor and elaborates
Bovis, Christopher H.
core  

EVOLUCIÓN DE LAS CONDICIONES SOCIOECONÓMICAS DE LOS HOGARES EN EL PROGRAMA OPORTUNIDADES

El Trimestre Económico, 2013
Este artículo muestra evidencia empírica que permite comprender cómo evolucio-na el bienestar de los hogares beneficiarios del programa de transferencias mone-tarias condicionadas Oportunidades en el corto y mediano plazos.
Raymundo M. Campos-Vázquez, Carlos Chiapa, Curtis Huffman, Alma S. Santillán H.   +3 more
doaj  

New High‐Tc Charge‐Transfer Multiferroicity in the Quasi‐2D Antiferromagnet CrSbS3

Advanced Science, EarlyView.
ABSTRACT Low‐dimensional magnets, particularly 2D systems, offer a rich platform for realizing unconventional multiferroic mechanisms, especially when multiple polarization channels coexist. In the quasi‐2D antiferromagnet CrSbS3, which crystallizes in the centrosymmetric orthorhombic space group Pnma and orders magnetically at TN ≈ 90 K, two ...
Hung‐Cheng Wu, Yu‐Hsin Liao, Chih‐Chung Tsai, Pei‐Ying Yang, Yu‐Hao Chang, Yu‐Hui Liang, D. Chandrasekhar Kakarla, Ajay Tiwari, C. Dhanasekhar, Chin‐Wei Wang, Daisuke Okuyama, Chia‐Nung Kuo, Chin‐Shan Lue, Tzu‐Hsuan Weng, Kung‐Hsuan Lin, Jau‐Wern Chiou, Chi‐Hung Lee, Hung‐Duen Yang   +17 more
wiley   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

Advanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan, Keshav Gajendra Babu, Markus Mukenhirn, Antje Garside, Vinita Ajit Kini, Trishla Adhikari, Timon Beck, Byung Ho Lee, Kyoohyun Kim, Carsten Werner, Raimund Schlüßler, Alf Honigmann, Sebastian Aland, Anna Verena Taubenberger   +13 more
wiley   +1 more source

ANÁLISE PRELIMINAR DA QUALIDADE DAS ÁGUAS DO AQUÍFERO LIVRE NO MUNICÍPIO DE SÃO JOÃO DA BARRA, RJ

Revista Águas Subterrâneas, 2015
O presente trabalho foi realizado no município de São João da Barra (SJB), Norte do Estado do Rio de Janeiro que se localiza na Bacia Sedimentar de Campos, e representa o maior potencial hídrico subterrâneo do Estado.
Flavio Costa de Cerqueira, Maria da Gloria Alves, Zélia Maria Peixoto Chrispim, Felipe Fraga de Almeida, Lyndemberg Campelo Correia, Gerson Cardoso da Silva Júnior   +5 more
doaj  

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

EFECTO DE LA VENTILACIÓN NATURAL EN EL CONSUMO ENERGÉTICO DE UN EDIFICIO BIOCLIMÁTICO. ANÁLISIS Y ESTUDIO MEDIANTE ENERGY PLUS.

Revista Hábitat Sustentable, 2018
El enfriamiento pasivo a través de la ventilación natural presenta un gran potencial para viviendas unifamiliares en climas templados continentales como lo es la ciudad de Mendoza, ubicada al centro oeste de la República Argentina.
María Victoria Mercado, Gustavo Barea, Alfredo Esteves, Celina Filippín   +3 more
doaj  

Assisted protein folding at low temperature: evolutionary adaptation of the Antarctic fish chaperonin CCT and its client proteins

Biology Open, 2014
Eukaryotic ectotherms of the Southern Ocean face energetic challenges to protein folding assisted by the cytosolic chaperonin CCT. We hypothesize that CCT and its client proteins (CPs) have co-evolved molecular adaptations that facilitate CCT–CP ...
Jorge Cuellar, Hugo Yébenes, Sandra K. Parker, Gerardo Carranza, Marina Serna, José María Valpuesta, Juan Carlos Zabala, H. William Detrich   +7 more
doaj   +1 more source

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

The Association of Central corneal thickness with Intra-ocular Pressure and Refractive Error in a Nigerian Population [PDF]

, 2008
The purpose of this study was to determine the variation of central corneal thickness (CCT) with intraocular pressure (IOP) and spherical equivalent refractive error.
Iyamu, Eghosasere, Memeh, Misan
core   +1 more source