Results 111 to 120 of about 368,667 (267)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Assessment of Alinity s Chagas^® as a Primary Diagnostic Test for Chronic Chagas Disease in a Non-Endemic Area of Europe (Barcelona, Spain)

Life
Chagas disease (CD) has become a worldwide problem due to globalization. In Europe, most cases are imported and are diagnosed in the chronic phase by two serological tests, as recommended by the World Health Organization.
Alba Abras, Cristina Ballart, Anna Fernández-Arévalo, Teresa Llovet, Montserrat Gállego, Carmen Muñoz   +5 more
doaj   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

The potential of Red Supergiants as extra-galactic abundance probes at low spectral resolution

, 2010
Red Supergiants (RSGs) are among the brightest stars in the local universe, making them ideal candidates with which to probe the properties of their host galaxies.
Ben Davies, Bresolin, Carr, Chiavassa, Cunha, Davies, Davies, Donald F. Figer, Garnett, Gustafsson, Humphreys, Josselin, Kewley, Kudritzki, Kudritzki, Lambert, Levesque, Meynet, Origlia, Plez, Rayner, Rolf-Peter Kudritzki, Schwarzschild, U, Wallace   +24 more
core   +1 more source

The Effect of Purcell Cavities on the Lifetime of Thermally Activated Delayed Fluorescent Emitters

Advanced Functional Materials, EarlyView.
A pressing challenge to OLED displays and lighting is to balance high efficiency and long operational lifetime in the deep blue spectrum. The Purcell effect can reduce the triplet density and hence the probability for destructive energy‐driven triplet annihilation events that limit the OLED lifetime. Here we study of the Purcell effect on two different
Sritoma Paul, Haonan Zhao, Collin N. Muniz, Mark E. Thompson, Stephen R. Forrest   +4 more
wiley   +1 more source

Diagnostic Value of Perinuclear Antineutrophil Cytoplasmic Antibody and Anti-Saccharomyces Cerevisiae Antibody and their Relationship with inflammatory Bowel disease Characteristics in Iranian Patients [PDF]

Iranian Journal of Public Health, 2005
Introduction: Inflammatory bowel disease (IBD) has two major groups: Ulcerative Colitis (UC) and Crohn’s Disease (CD), diagnosed by routine invasive methods.
M Aarabi, A Bahari, M Hedayati, A Jarollahi, M Habibi, R Aghazadeh, MR Zali   +6 more
doaj   +1 more source

Broadband, Flexible, Skin‐Compatible Carbon Dots/Graphene Photodetectors for Wearable Applications

Advanced Functional Materials, EarlyView.
Broadband, flexible photodetectors integrating nitrogen‐rich carbon dots with single‐layer graphene on plastic substrates are demonstrated. A biocompatible chitosan–glycerol electrolyte enables efficient low‐voltage gating and on‐skin operation. The devices exhibit ultraviolet‐to‐near‐infrared response, mechanical robustness under bending, and verified
Nouha Loudhaief, Petr Rozhin, Ilaria Bertuol, Ali Raza, Leonardo Viti, Subhankar Roy, Enrico Cavarzerani, Luca Sbuelz, Matteo Brilli, Andrea Serinolli, Jacopo Nicoletti, Riccardo Piccoli, Sebastián Castilla, Simone Dal Zilio, Enrique Rodríguez‐Castellón, Miriam Serena Vitiello, Maurizio Selva, Flavio Rizzolio, Alvise Perosa, Giovanni Antonio Salvatore, Domenico De Fazio   +20 more
wiley   +1 more source

Adiponectin and HMW Oligomers in Relation to Inflammatory Markers in Crohn’s Disease Patients

Biomedicines
Background/Objectives: Crohn’s disease (CD), a chronic inflammatory gastrointestinal illness, is the result of genetics and environmental factors. Adipose tissue has recently been found to play a significant role in CD.
Maurizio Marra, Marta Mallardo, Ersilia Nigro, Iolanda Cioffi, Camilla Leo, Alessia Dalila Guarino, Fabiana Castiglione, Fabrizio Pasanisi, Aurora Daniele   +8 more
doaj   +1 more source

Non-local energetics of random heterogeneous lattices

, 2010
In this paper, we study the mechanics of statistically non-uniform two-phase elastic discrete structures. In particular, following the methodology proposed in (Luciano and Willis, Journal of the Mechanics and Physics of Solids 53, 1505-1522, 2005 ...
Alava, Alicandro, Alicandro, Arndt, Arnoux, Bardenhagen, Bažant, Berezhnyy, Blanc, Blanc, Blanc, Blanc, Blanc, Bouchitté, Braides, Braides, Braides, Bronkhorst, Christensen, Chudoba, Cusatis, Dvorak, Eringen, Francfort, Friesecke, Ganghoffer, Gavinia, Grassl, Hashin, Horn, Ibrahimbegovic, Iosifescu, Jagla, Jan Zeman, Jiao, Jirásek, Lilliu, Luciano, Luciano, Marc G.D. Geers, Martinsson, Miehe, Mielke, Mielke, Miller, Milton, Ostoja-Starzewski, Ostoja-Starzewski, Padberg, Pradel, Quintanilla, Rinaldi, Ron H.J. Peerlings, Roscoe, Sharif-Khodaei, Tadmor, Torquato, Triantafyllidis, Vellinga, Vořechovský, Willis, Willis   +61 more
core   +2 more sources