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Molecular cloning and expression analysis of pig CD138
Research in Veterinary Science, 2013CD138 (syndecan-1) interacts with various components of the extracellular matrix and associates with the actin cytoskeleton. In this study, we cloned pig CD138 cDNA and determined its complete cDNA sequence. Pig CD138 cDNA contained an open reading frame (930 bp) encoding 309 amino acids with five well conserved putative glycosaminoglycan attachment ...
Joonbeom, Bae +7 more
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A case of CD138-/CD19+/CD4+ IgD plasma cell leukemia
Cytometry Part B: Clinical Cytometry, 2014Background: Plasma cell leukemia (PCL) is an uncommon and aggressive disease caused by the clonal proliferation of atypical plasma cells with phenotypical abnormalities similar to those seen in multiple myeloma (MM), although at different rates. Here we report a case of IgD PCL with a very unusual CD138-/CD19+/CD4+ phenotype Methods: Peripheral blood ...
Sorigue M +5 more
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Blood, 2015
Abstract INTRODUCTION. Although remarkable advances have been reported in Multiple Myeloma (MM) therapy, mainly due to the introduction of novel agents, the disease remains incurable in most of the patients. The iperactivation of self-renewal mechanisms, like Hedgehog (Hh) pathway, which controls the refuel of the tumor clone, might be ...
Marina Martello +13 more
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Abstract INTRODUCTION. Although remarkable advances have been reported in Multiple Myeloma (MM) therapy, mainly due to the introduction of novel agents, the disease remains incurable in most of the patients. The iperactivation of self-renewal mechanisms, like Hedgehog (Hh) pathway, which controls the refuel of the tumor clone, might be ...
Marina Martello +13 more
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CD138/syndecan–1 in pancreatic solid and pseudopapillary neoplasms
Journal of Clinical Pathology, 2018Solid and pseudopapillary neoplasms (SPNs) are rare tumours, their histogenesis is still a matter of debate. These tumours are reported to express CD-type proteins such as CD10, CD56 and CD99.1 We have recently observed another CD-type protein expression, that of CD138/syndecan-1, frequently used to point out a plasma cell differentiation.
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Functional properties of CD138- and CD138+ cells in Multiple Myeloma: Study in the 5T33MM model
2011Multiple myeloma (MM) contains a heterogenous mix of tumor cells including CD138- and CD138+ cells. While some studies described that CD138- cells are a minor population containing MM clonogenic and therapy-resistant cells, others show that only CD138+ cells are able to proliferate and engraft.
Van Valckenborgh, Els +7 more
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The significance of soluble CD138 in diagnosis of monoclonal gammopathies.
Neoplasma, 2006Report is summary of the results of study designed to ascertain the significance of soluble CD138 (sCD138) assessment in patients with different monoclonal gammopathies. Previous studies have shown that sCD138 is shed from the surface of myeloma cells into serum and that this marker is a new independent prognostic parameter in multiple myeloma.
V, Maisnar +6 more
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Ki67 AND CD138/SYNDECAN-1 IMMUNOEXPRESSION IN AMELOBLASTOMAS
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2023Allan Vinícius MARTINS-DE-BARROS +6 more
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