Radiotherapy Upregulates the Expression of Membrane-Bound Negative Complement Regulator Proteins on Tumor Cells and Limits Complement-Mediated Tumor Cell Lysis. [PDF]
Liang Y+5 more
europepmc +1 more source
Predictive factors and nomogram for the risk of cytokine release syndrome with anti-CD3 × CD20 bispecific antibodies for Chinese patients. [PDF]
Sun P+13 more
europepmc +1 more source
Expression of IL‐4 Receptor Alpha in Ectopic Lymphoid Tissue in Chronic Rhinosinusitis
Allergy, EarlyView.
Kengo Kanai+9 more
wiley +1 more source
This study shows that components of the ESCRT‐III membrane repair machinery, VPS4B and CHMP2A, are dysregulated in progressive MS and are associated with higher neurodegeneration and inflammation. This might lead to improper function of the complex to inhibit the final stages of necroptosis activation and thus impede neuronal cell death.
Carmen Picon+5 more
wiley +1 more source
Bright-Field Multiplex Immunohistochemistry in Swine PCV2 and PRRSV Lymphadenopathies. [PDF]
D'Annunzio G+10 more
europepmc +1 more source
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen+3 more
wiley +1 more source
Secondary Organising Pneumonia Among Immunocompromised Multiple Sclerosis Patients Treated With Ocrelizumab Following COVID-19 Infection: Two Case Reports With Literature Review. [PDF]
Aljarod TM, Morehead RS.
europepmc +1 more source
Artificial intelligence streamlines scientific discovery of drug–target interactions
Abstract Drug discovery is a complicated process through which new therapeutics are identified to prevent and treat specific diseases. Identification of drug–target interactions (DTIs) stands as a pivotal aspect within the realm of drug discovery and development. The traditional process of drug discovery, especially identification of DTIs, is marked by
Yuxin Yang, Feixiong Cheng
wiley +1 more source
B cell-extrinsic and intrinsic factors linked to early immune repletion after anti-CD20 therapy in patients with multiple sclerosis of African ancestry. [PDF]
Silverman GJ+6 more
europepmc +1 more source