Results 301 to 310 of about 168,682 (384)

PI3Kδ Inhibitor Parsaclisib in Japanese Patients With Relapsed or Refractory Follicular Lymphoma

Cancer Science, EarlyView.
CITADEL‐213 evaluated the efficacy and safety of parsaclisib (PI3Kδ inhibitor) in Japanese patients with relapsed or refractory follicular lymphoma (R/R FL). The objective response rate was 88.1%, with 23.8% of patients experiencing a complete response and 64.3% experiencing a partial response; treatment‐emergent adverse events led to parsaclisib ...
Noriko Fukuhara, Isao Yoshida, Takuro Ishiguro, Katsuya Fujimoto, Junya Kuroda, Toshiki Uchida, Ryusuke Yamamoto, Yoshiaki Ogawa, Yasushi Hiramatsu, Toshiro Ito, Seiichiro Katagiri, Tomonori Nakazato, Kazumi Suzukawa, Kenzo Kinami, Mi Zhou, Eiju Negoro   +15 more
wiley   +1 more source

Advancing Treatment in Pediatric Multiple Sclerosis: The Promise of B-Cell-Targeting Therapies. [PDF]

Int J Mol Sci
Skarlis C, Kotsari M, Anagnostouli M.
europepmc   +1 more source

CXCL13 and CCL21 Induce Tertiary Lymphoid Structures and Enhance the Efficacy of Immunotherapy for Melanoma

Cancer Science, EarlyView.
Plasma CCL21 levels were significantly increased in tertiary lymphoid structures (TLS)‐positive melanoma cases both before and after immune checkpoint inhibitors (ICI) treatment, while CXCL13 levels were significantly elevated after ICI treatment. We successfully induced TLS by co‐administering CXCL13 and CCL21 in a mouse melanoma model, clarifying ...
Maki Yoshimitsu, Motoki Nakamura, Shinji Kano, Tetsuya Magara, Hiroshi Kato, Aiko Sakai, Masaya Sugiyama, Masashi Mizokami, Akimichi Morita   +8 more
wiley   +1 more source

Novel immunotherapies for immune-mediated haemolytic anaemia in dogs and people [PDF]

, 2015
Aerts, Ahmad, Andre, Baek, Baker, Baluna, Barcellini, Bardwell, Barker, Barker, Barker, Bennett, Berentsen, Bielekova, Brode, Brunkow, Buckner, Cancro, Cao, Castela, Corato, Den Otter, Desreumaux, Dieckmann, Dowling, Ellis, Forrester, Gagliani, Garden, Ginzler, Graca, Grant, Grundy, Haagsman, Haase, Hall, Hall, Han, Herzog, Heylmann, Hoffmann, Hori, Hori, Humrich, Impellizeri, Ito, James W Swann, Jubala, Jutel, Keiserman, Kim, Klatzmann, Knueppel, Kojima, Komatsu, Konietschke, Lutz, Mahevas, Mahevas, Marek-Trzonkowska, Mason, McCullough, Meiler, Miller, Miyara, Mouchess, Moyo, Mqadmi, Mueller, Oliver A Garden, Olivry, Packman, Penalver, Pinheiro, Polyak, Putnam, Reff, Reimer, Reynaud, Ring, Rodriguez, Rose, Rosenstein, Rue, Saadoun, Sabatos-Peyton, Sadlack, Sadlack, Sakaguchi, Schabowsky, Sharfe, Singer, Swann, Swann, Thornton, Tischner, Verhagen, Volkmann, Waldron-Lynch, Ward, Whitley, Wildin, Willerford, Wing, Xiao, Xu, Xu, Yadav, Zaja, Zanella, Zhao, Ziekman   +111 more
core   +1 more source

CD20 and CD19 promote proliferation driven by the IgM-TLR9-L265P MyD88 complex. [PDF]

Int Immunol
Kobayashi Y, Sato R, Shimizu Y, Fukui R, Shibata T, Tsukamoto H, Tsubata T, Miyake K.   +7 more
europepmc   +1 more source

Vitrectomy as a rapid diagnostic tool for lymphoma: Cytology and flow cytometry approach

British Journal of Haematology, EarlyView.
Pierre Gascon, Diane Frankel, Shirley Fritz, Alban Comet, Frédéric Matonti, Prithvi Ramtohul, John Conrath, Thierry David, Philippe Robert, Laurence Schenone, Vincent Harlay, Olivier Chinot, Emeline Tabouret, Isabelle Nanni, Alexandre Astier, Patrice Roll, Elise Kaspi   +16 more
wiley   +1 more source

Aging and Multiple Sclerosis

Clinical and Experimental Neuroimmunology, EarlyView.
ABSTRACT Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease. While typically diagnosed in young adults, late‐onset MS (LOMS, onset > 50 years) is becoming increasingly recognized, presenting with distinct features such as higher rates of progressive onset and motor symptoms.
Takuya Matsushita
wiley   +1 more source

Review: radiotherapy-mediated B cells within the TLS influence the tumor microenvironment. [PDF]

J Immunother Cancer
Yang H, Chen K, Meng Y, Chen Z, Xu Y, Zhou D, Zhou S, Zhang X.   +7 more
europepmc   +1 more source

Production and Functional Verification of 8‐Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)‐Edited Donor Pigs for Xenotransplantation

Cell Proliferation, EarlyView.
Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang, Kaixiang Xu, Tao Liu, Heng Zhao, Muhammad Ameen Jamal, Gen Chen, Xiaoying Huo, Chang Yang, Deling Jiao, Taiyun Wei, Hanfei Huang, Hongfang Zhao, Jianxiong Guo, Fengchong Wang, Xiong Zhang, Kai Liu, Siming Qu, Gang Wang, Hui Guo, Gang Chen, Hong‐Ye Zhao, Zhong Zeng, Kefeng Dou, Hong‐Jiang Wei   +23 more
wiley   +1 more source

Rituximab efficacy for minimal residual disease eradication in philadelphia-negative acute lymphoblastic leukemia CD20. [PDF]

Ann Hematol
Cecchi N, Sciumè M, Ricchiuti A, Bosi A, Tagliaferri E, Passamonti F, Fracchiolla NS.   +6 more
europepmc   +1 more source