Results 321 to 330 of about 180,829 (383)

Selumetinib as an Effective Therapy of Histiocytic Sarcoma Evolving From a B‐Cell Acute Lymphoblastic Leukaemia

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction Histiocytic sarcoma (HS) is a rare neoplasm derived from non‐Langerhans histiocytic cells, exceptionally arising from B‐ALL. Methods We present the case of a child with high‐risk B‐ALL with PAX5 P80R mutation. Results Despite initial remission, a chemoresistant paravertebral mass was identified as HS.
Laetitia Largeaud   +12 more
wiley   +1 more source

Identification of an Elusive CBFA2T3::GLIS2 Fusion Variant in Acute Megakaryoblastic Leukemia by Whole Genome Sequencing

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Advancements in genomic profiling have significantly improved the classification and treatment strategies for acute myeloid leukemia (AML). However, widely utilized molecular diagnostic techniques, including targeted gene panels, are often insufficient for detecting complex structural variants, cryptic fusions, and poorly characterized driver ...
Yuna Lee   +12 more
wiley   +1 more source

CD56<sup>bright</sup>NK cells are negatively associated with antibody response to vaccination in people with multiple sclerosis on B-cell-depleting therapy. [PDF]

open access: yesClin Transl Immunology
Perkins GB   +21 more
europepmc   +1 more source

Clinical Profile and Chemotherapy Outcomes of Adult Lymphoma Patients at Jimma University Medical Center: A 2‐Year Retrospective Study

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Background Lymphoma, including Hodgkin (HL) and non‐Hodgkin (NHL) subtypes, is a leading non‐infectious cause of morbidity and mortality in Ethiopia. Diagnosis relies on histopathology with immunohistochemistry or flow cytometry; staging and prognosis use laboratory tests and imaging.
Kisi Chemeda Gutema   +8 more
wiley   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

open access: yesMedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

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