Results 101 to 110 of about 778 (150)

African swine fever virus Armenia/07 virulent strain controls interferon beta production through the cGAS-STING pathway [PDF]

open access: yes, 2019
African swine fever virus (ASFV) is a complex, cytoplasmic double-stranded DNA (dsDNA) virus that is currently expanding throughout the world. Currently, circulating virulent genotype II Armenia/07-like viruses cause fatal disease in pigs and wild boar ...
García-Belmonte, Raquel   +4 more
core   +1 more source

Preparation and epitope analysis of monoclonal antibodies against African swine fever virus DP96R protein

open access: yesBMC Veterinary Research
Background Many proteins of African swine fever virus (ASFV, such as p72, p54, p30, CD2v, K205R) have been successfully expressed and characterized. However, there are few reports on the DP96R protein of ASFV, which is the virulence protein of ASFV and ...
Chao Li   +11 more
doaj   +1 more source

Modulation of MHC class I expression by African swine fever virus and the role of virus proteins EP153R and CD2v

open access: yes, 2014
Various DNA viruses, including pox- and herpesviruses, express proteins which down-regulate host MHC class I antigen expression as an immune evasion strategy. Previous studies into whether ASFV modulates expression of the porcine MHC class I molecule, SLA I, have not provided a clear answer. In this thesis, the effect of African swine fever virus (ASFV)
openaire   +3 more sources

Towards Safe African Swine Fever Vaccines: The A137R Gene as a Tool to Reduce Virulence and a Promising Serological DIVA Marker Candidate

open access: yesAnimals
African swine fever (ASF) is an emerging disease caused by the African swine fever virus (ASFV), which is a great threat to the swine industry worldwide.
Andrey Koltsov   +7 more
doaj   +1 more source

Development of Adenovirus-vectored Prototype Vaccines for African Swine Fever Virus and Bovine Viral Diarrhea Virus [PDF]

open access: yes, 2017
The objective of this work was to develop adenovirus-vectored prototype vaccines against two pathogens, African Swine Fever Virus (ASFV) and Bovine Viral Diarrhea Virus (BVDV), which cause disease in two major livestock species, swine and cattle ...
Lokhandwala, Shehnaz Taher
core  

Deletion of B125R increases protection induced by a genotype II African swine fever vaccine candidate

open access: yesnpj Vaccines
A modified live attenuated African swine fever genotype II virus, GΔDKE-CmutQ96R/K108D, with deletions of three genes, DP148R, EP153R, and K145R and expressing a mutated CD2v protein with a non-haemadsorbing phenotype, was further modified by first ...
Anusyah Rathakrishnan   +7 more
doaj   +1 more source

How Does African Swine Fever Virus Evade the cGAS-STING Pathway?

open access: yesPathogens
African swine fever (ASF), a highly infectious and devastating disease affecting both domestic pigs and wild boars, is caused by the African swine fever virus (ASFV). ASF has resulted in rapid global spread of the disease, leading to significant economic
Can Lin   +5 more
doaj   +1 more source

Emerg Infect Dis [PDF]

open access: yes
African swine fever is widespread in Africa but has occasionally been introduced into other continents. In June 2007, African swine fever was isolated in the Caucasus Region of the Republic of Georgia and subsequently in neighboring countries (Armenia ...

core  

Evaluation and comparison of African swine fever virus and vaccinia virus cell entry pathways [PDF]

open access: yes
Doctor of PhilosophyDepartment of Diagnostic Medicine/PathobiologyRaymond R. R. RowlandAfrican swine fever virus (ASFV) causes a highly contagious and deadly disease in swine, with severe economic consequences.
Olcha, Matthew Evan
core  

African swine fever: advances and challenges [PDF]

open access: yes
African swine fever (ASF) has become a major focus of research after spreading to four continents besides Africa. In its natural African ecosystem, the causative ASF virus (ASFV) is maintained by indigenous Suidae as natural reservoirs and hard tick ...
Blome, S.   +2 more
core   +1 more source

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