Results 1 to 10 of about 70,035 (260)

Genotype I African swine fever viruses emerged in domestic pigs in China and caused chronic infection

Emerging Microbes and Infections, 2021
The Georgia-07-like genotype II African swine fever virus (ASFV) with high virulence has been prevalent in China since 2018. Here, we report that genotype I ASFVs have now also emerged in China. Two non-haemadsorbing genotype I ASFVs, HeN/ZZ-P1/21 and SD/
Encheng Sun, Lianyu Huang, Xianfeng Zhang, Jiwen Zhang, Dongdong Shen, Zhenjiang Zhang, Zilong Wang, Hong Huo, Wenqing Wang, Haoyue Huangfu, Wan Wang, Fang Li, Renqiang Liu, Jianhong Sun, Zhijun Tian, Wei Xia, Yuntao Guan, Xijun He, Yuanmao Zhu, Dongming Zhao, Zhigao Bu   +20 more
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Cyclophilin A stabilizes the capsid protein p72 to facilitate African swine fever virus replication [PDF]

Nature Communications
African swine fever virus (ASFV) is a large DNA virus that poses a major threat to the global swine industry. Its virion is encapsulated by an icosahedral capsid predominantly composed of the structural protein p72, which constitutes approximately one ...
Hui Kong, Liqin Yang, Zhenjiang Zhang, Ying Zhang, Linlin Liu, Wan Wang, Linfei Song, Yuanmao Zhu, Encheng Sun, Fang Li, Zhigao Bu, Xiangpeng Sheng, Dongming Zhao   +12 more
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Attenuated African swine fever viruses and the live vaccine candidates: a comprehensive review

Microbiology Spectrum
The African swine fever virus (ASFV) is spreading worldwide and causing huge economic losses to the global pig industry. The ASFV genome is 170–193 kb in length, contains approximately 150 open reading frames, and encodes more than 200 proteins, most of ...
Jiaqi Fan, Haisheng Yu, Faming Miao, Junnan Ke, Rongliang Hu   +4 more
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The CP312R protein of African swine fever virus inhibits host protein translation via the BiP/PERK/eIF2α pathway [PDF]

Veterinary Research
African swine fever is a highly contagious, febrile, hemorrhagic, and often fatal disease of domestic pigs and wild boar, caused by African swine fever virus (ASFV). ASFV has evolved multiple strategies to suppress host antiviral responses, including the
Jingwen Dai, Pingping Zhou, Yanjin Wang, Haojie Ren, Kehui Zhang, Meilin Li, Hailiang Ge, Hongwei Cao, Jiaqi Li, Hao Deng, Wen-Rui He, Lian-Feng Li, Su Li, Hua-Ji Qiu   +13 more
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Detection of a Novel African Swine Fever Virus with Three Large-Fragment Deletions in Genome, China

Microbiology Spectrum, 2022
We reported a novel African swine fever virus (ASFV) strain that had a three-large-fragment deletion and unique variations in genome. This isolate displayed a nonhemadsorbing phenotype and had homogeneous proliferation compared with the wild-type ASFV ...
Yankuo Sun, Zhiying Xu, Han Gao, Sijia Xu, Jing Liu, Jiabao Xing, Qiyuan Kuang, Yang Chen, Heng Wang, Guihong Zhang   +9 more
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Whole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutations

Frontiers in Veterinary Science, 2023
IntroductionSince the first report of outbreaks of African swine fever (ASF) in Georgia in 2007, the disease has expanded into Europe, Russia, and Asia, spreading rapidly via contact with infected animals including domestic pigs and wild boars.
Ali Mazloum, Antoinette van Schalkwyk, Antoinette van Schalkwyk, Andrey Shotin, Nikolay Zinyakov, Alexey Igolkin, Roman Chernishev, Zoran Debeljak, Fedor Korennoy, Alexander V. Sprygin   +9 more
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Comparative Analysis of Full Genome Sequences of African Swine Fever Virus Isolates Taken from Wild Boars in Russia in 2019

Pathogens, 2021
In this study, we report on the full genome phylogenetic analysis of four ASFV isolates obtained from wild boars in Russia. These samples originated from two eastern and two western regions of Russia in 2019.
Ali Mazloum, Antoinette van Schalkwyk, Andrey Shotin, Alexey Igolkin, Ivan Shevchenko, Konstantin N. Gruzdev, Natalia Vlasova   +6 more
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Genetic Characterization of the Central Variable Region in African Swine Fever Virus Isolates in the Russian Federation from 2013 to 2017

Pathogens, 2022
African swine fever virus (ASFV), classified as genotype II, was introduced into Georgia in 2007, and from there, it spread quickly and extensively across the Caucasus to Russia, Europe and Asia. The molecular epidemiology and evolution of these isolates
Ali Mazloum, Antoinette Van Schalkwyk, Roman Chernyshev, Andrey Shotin, Fedor I. Korennoy, Alexey Igolkin, Alexander Sprygin   +6 more
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Interaction network of African swine fever virus structural protein p30 with host proteins

Frontiers in Microbiology, 2022
African swine fever virus (ASFV) is a complex nucleocytoplasmic large DNA virus (NCLDV) that causes a lethal hemorrhagic disease that is currently threatening the global pig industry. ASFV structural protein p30 is a membrane phosphoprotein that suggests
Xiongnan Chen, Xiongnan Chen, Xiongnan Chen, Xiaojun Chen, Xiaojun Chen, Xiaojun Chen, Yifan Liang, Yifan Liang, Yifan Liang, Sijia Xu, Sijia Xu, Sijia Xu, Zhijun Weng, Zhijun Weng, Qi Gao, Qi Gao, Qi Gao, Zhao Huang, Zhao Huang, Zhao Huang, Guihong Zhang, Guihong Zhang, Guihong Zhang, Guihong Zhang, Guihong Zhang, Lang Gong, Lang Gong, Lang Gong   +27 more
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Evaluation of African Swine Fever Virus E111R Gene on Viral Replication and Porcine Virulence

Viruses, 2023
African swine fever (ASF) is an acute infectious disease of domestic pigs and wild boars caused by the African swine fever virus (ASFV), with up to a 100% case fatality rate. The development of a vaccine for ASFV is hampered by the fact that the function
Xintao Zhou, Jiaqi Fan, Yanyan Zhang, Jinjin Yang, Rongnian Zhu, Huixian Yue, Yu Qi, Qixuan Li, Yu Wang, Teng Chen, Shoufeng Zhang, Rongliang Hu   +11 more
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