Results 21 to 30 of about 1,740,141 (209)

African Swine Fever Virus (ASFV): Immunity and Vaccine Development

, 2023
African swine fever virus (ASFV) is the causative agent of the highly contagious disease African swine fever (ASF), which can result in mortality rates of up to 100% in pigs infected by virulent strains [...
Jong-Soo Lee (194708), Kiramage Chathuranga (7245233)   +1 more
core   +2 more sources

A Triplex PCR Method for Distinguishing the Wild-Type African Swine Fever Virus From the Deletion Strains by Detecting the Gene Insertion

Frontiers in Veterinary Science, 2022
To date, there is no effective vaccine or antiviral therapy available to prevent or treat African swine fever virus (ASFV) infections. ASFV gene deletion strains have been proposed as promising anti-ASFV vaccine candidates.
Zhao Huang, Zhao Huang, Zhiying Xu, Zhiying Xu, Haoxuan Cao, Haoxuan Cao, Fanliang Zeng, Fanliang Zeng, Heng Wang, Heng Wang, Heng Wang, Lang Gong, Lang Gong, Shengxun Zhang, Sen Cao, Guihong Zhang, Guihong Zhang, Guihong Zhang, Guihong Zhang, Zezhong Zheng, Zezhong Zheng   +20 more
doaj   +1 more source

Identification and characterization of nanobodies specifically against African swine fever virus major capsid protein p72

Frontiers in Microbiology, 2022
African swine fever virus (ASFV) is a large and very complex DNA virus. The major capsid protein p72 is the most predominant structural protein and constitutes the outmost icosahedral capsid of the virion.
Jifei Yang, Mengyao Jing, Qingli Niu, Jinming Wang, Yaru Zhao, Yaru Zhao, Meng Liu, Guiquan Guan, Jianxun Luo, Hong Yin, Hong Yin, Zhijie Liu, Zhijie Liu   +12 more
doaj   +1 more source

African swine fever

Uirusu, 2020
African swine fever (ASF) is a hemorrhagic infectious disease of Suids, which is endemic in sub-Saharan area of African continent. ASF is usually circulating sub-symptomatically among wild species of Suidae family, such as warthogs and bush pigs, by mediating Ornithodoros soft ticks.
openaire   +3 more sources

Spatiotemporally Orchestrated Interactions between Viral and Cellular Proteins Involved in the Entry of African Swine Fever Virus

Viruses, 2021
African swine fever (ASF) is a highly contagious hemorrhagic disease in domestic pigs and wild boars with a mortality of up to 100%. The causative agent, African swine fever virus (ASFV), is a member of the Asfarviridae family of the nucleocytoplasmic ...
Kehui Zhang, Su Li, Sheng Liu, Shuhong Li, Liang Qu, George F. Gao, Hua-Ji Qiu   +6 more
doaj   +1 more source

African Swine Fever Virus: A Review [PDF]

Viruses, 2017
African swine fever (ASF) is a highly contagious viral disease of swine which causes high mortality, approaching 100%, in domestic pigs. ASF is caused by a large, double stranded DNA virus, ASF virus (ASFV), which replicates predominantly in the cytoplasm of macrophages and is the only member of the Asfarviridae family, genus Asfivirus.
Inmaculada Galindo, Covadonga Alonso
openaire   +3 more sources

2. African swine fever virus: cellular and molecular aspects [PDF]

, 2021
Over the last years, African swine fever virus (ASFV) has spread to several European and Asian countries, presently showing an unprecedented geographic distribution.
Gallardo, C., F. Ferreira, Alonso, C., Andrés, G., C. Alonso, A.S. Olesen, Karger, Axel, Urbano, A., H. Zakaryan, Arabyan, E., Forth, Jan Hendrik, A. Malogolovkin, L. Dixon, Olesen, A. S., Zakaryan, H., G. Cackett, Wang, X., G. Andrés, C. Gallardo, F. Werner, I. Galindo, X. Wang, E. Arabyan, J.H. Forth, Galindo, I., S. Blome, Dixon, L., Blome, Sandra, A. Urbano, T.B. Rasmussen, A. Karger, Werner, F., Perez-Nuñez, D., Y. Revilla, Cackett, G., Ferreira, F., Rasmussen, T. B., Revilla, Y., Malogolovkin, A., D. Perez-Nuñez   +39 more
core   +1 more source

Swine Interferon-Inducible Transmembrane Proteins Potently Inhibit African Swine Fever Virus Replication

Frontiers in Immunology, 2022
African swine fever virus (ASFV) causes an acute, hemorrhagic, and highly contagious disease in domestic swine, leading to significant economic losses to the global porcine industry.
Siqi Cai, Siqi Cai, Siqi Cai, Zezhong Zheng, Zezhong Zheng, Zezhong Zheng, JiaoJiao Cheng, JiaoJiao Cheng, JiaoJiao Cheng, Lintao Zhong, Lintao Zhong, Lintao Zhong, Ran Shao, Ran Shao, Ran Shao, Feiyan Zheng, Feiyan Zheng, Feiyan Zheng, Zhiying Lai, Zhiying Lai, Zhiying Lai, Jiajun Ou, Jiajun Ou, Jiajun Ou, Liang Xu, Liang Xu, Liang Xu, Pei Zhou, Pei Zhou, Pei Zhou, Gang Lu, Gang Lu, Gang Lu, Guihong Zhang, Guihong Zhang, Guihong Zhang   +35 more
doaj   +1 more source

Classical and African swine fever in domestic pigs and European wild boar [PDF]

, 2012
Classical and African swine fever are highly contagious, notifiable viral diseases affecting different members of the Suidae family, both showing tremendous impact on animal health and pig production.
Gabriel, Claudia
core   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +2 more sources