Results 141 to 150 of about 778 (150)

Development and characterization of recombinant ASFV CD2v protein nanoparticle-induced monoclonal antibody

International Journal of Biological Macromolecules, 2022
African swine fever (ASF) caused by African swine fever virus (ASFV) is becoming a serious threat to the swine industry worldwide. CD2v is a key pathogenic factor of ASFV and the protective antigen with low immunogenicity, whereas viral protein-based nanoparticles have advantages of precise assembly and high immunogenicity.
Dongna Ren, Peiyang Ding, Siyuan Liu, Ning Zhang, Yilan Chen, Qingmei Li, Fan Lü, Zejie Chang, Gaiping Zhang   +8 more
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Investigation of subunit vaccine candidates against african swine fever vaccine candidates derived from subdomains of the transmembrane protein CD2v, using immunoinformatics and molecular dynamics metods

Кристаллография / Crystallography Reports
African swine fever (ASF) remains a global threat to pig production, causing economic losses. In this study, a theoretical comparison of candidate subunit vaccines based on the ASFV transmembrane protein CD2v was performed. Three supramembrane subdomains of CD2v were evaluated using immunoinformatics, structure prediction and molecular modeling methods.
Anastasia Ivanovsky
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Development of Subunit Vaccine against African Swine Fever Virus Based on CD2v Protein Using Immunoinformatics and Molecular Dynamics Methods

Crystallography Reports
A. S. Ivanovsky, В. И. Тимофеев, А В Калач, Y. V. Kordonskaya, М. А. Марченкова, Yu. V. Pisarevsky, Y. A. Dyakova, M. V. Kovalchuk   +7 more
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Exploring In-Silico Immunoepitope Landscape and Genetic Diversity in p72 and CD2v Proteins Across Asian African Swine Fever Virus Isolates

Indian Journal of Microbiology
Kalpana Singh, Nagendra Nath Barman, Lukumoni Buragohain, Sachin Kumar, Yashpal Singh Malik   +4 more
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Investigation of Subunit Vaccine Candidates against African Swine Fever Virus Derived from Subdomains of the Transmembrane Protein CD2v Using Immunoinformatics and Molecular Dynamics Methods

Crystallography Reports
A. S. Ivanovsky, В. И. Тимофеев, A. A. Chernyavsky, A. A. Tulenev, Yu. V. Kordonskaya, М. А. Марченкова, Yu. V. Pisarevsky, Yu. A. Dyakova   +7 more
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Structure and functional analysis of the African Swine Fever virus encoded CD2v/EP402R protein and investigation of its role in virus persistence in pigs

2022
African swine fever is a viral haemorrhagic disease of domestic pigs and wild boar and is a serious threat to the economy of many countries. No vaccines are available to induce protection in pigs against this lethal disease. The most promising approach for vaccine development is the use of modified live attenuated vaccines (MLAV) and these can confer ...
openaire   +1 more source

Deletion of the CD2v Gene from the Genome of ASFV-Kenya-IX-1033 Partially Reduces Virulence and Induces Protection in Pigs

Viruses, 2022
Johanneke D Hemmink, Emmanuel Mulaya Khazalwa, Hussein M Abkallo   +2 more
exaly  

Identification of Two Novel Linear B Cell Epitopes on the CD2v Protein of African Swine Fever Virus Using Monoclonal Antibodies

Viruses, 2023
exaly  

λ-Carrageenan inhibits African swine fever virus infection potentially through its interaction with the viral envelope protein CD2v

Kun Han, Limeng Sun, Can Jin, Siqi Wan, Caiqin Cao, Yulu Yue, Man Lu, Xiaotong Wang, Yi Zheng, Hailong Liu, Yilin Guo, Dagang Tao, Jinxue Ruan, Liangliang Fu, Kan Ding, Shengsong Xie, Shuhong Zhao, Kexin Du, Guangli Yu, Guoyun Li, Wengang Chai, Jingyu Yan, Guiqing Peng, Mei Yu   +23 more
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Generation and Characterization of Recombinant Pseudorabies Virus Delivering African Swine Fever Virus CD2v and p54

International Journal of Molecular Sciences
Jianhui Wei, Chuancheng Liu, Qi Chen
exaly