Results 11 to 20 of about 7,202 (139)
CD30/CD30 Ligand and CD40/CD40 Ligand in Malignant Lymphoid Disorders
The International Journal of Biological Markers, 1999 CD30 and CD40 are members of the tumor necrosis factor (TNF) receptor family. These two receptors have pleiotropic biologic functions including induction of apoptosis and enhancing cell survival.
A. Younes, A. Carbone
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CD30 Ligand/CD30 Plays a Critical Role in Th17 Differentiation in Mice [PDF]
The Journal of Immunology, 2010 Abstract A CD30 ligand (CD30L; CD153) and its receptor, CD30, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily. These were expressed preferentially by activated CD4+T cells. In this paper, we show that CD44lowCD62hiCD4+ T cells from CD30L−/− or CD30−/− mice exhibited impaired differentiation ...
Xun, Sun +6 more
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Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines [PDF]
Blood, 1994 CD30 is a member of the tumor necrosis factor receptor superfamily. CD30 was originally described as a cell surface antigen on primary and cultured Hodgkin's and Reed-Sternberg cells. In this study, recombinant human CD30 ligand was expressed on the surface of CV-1/EBNA cells and tested for biologic activities on a variety of different CD30+ human ...
H J, Gruss +5 more
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Functional aspects of the CD30 gene in Hodgkin’s lymphoma and anaplastic large cell lymphoma
Oncology Reviews, 2011 Lymphomas are neoplasms of the human immune system and can be divided into two categories, Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL). Anaplastic large cell lymphoma (ALCL) is a form of NHL that shares a common distinctive feature with ...
Desiree S. Ho +2 more
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Frontiers in Immunology, 2017 CD30 is a tumor necrosis factor receptor (TNFR) family member whose expression is associated with Hodgkin’s disease, anaplastic large cell lymphomas, and other T and B lymphoproliferative disorders in humans. A limited number of studies have assessed the
Angela C. Zhou +3 more
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Extracellular matrix from porcine small intestinal submucosa (SIS) as immune adjuvants. [PDF]
PLoS ONE, 2011 Porcine small intestinal submucosa (SIS) of Cook Biotech is licensed and widely used for tissue remodeling in humans. SIS was shown to be highly effective as an adjuvant in model studies with prostate and ovarian cancer vaccines.
Youssef Aachoui, Swapan K Ghosh
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Indian Journal of Dermatology, 2011 The primary cutaneous T-cell lymphomas (CTCL) represent a clonal T-lymphocyte proliferation infiltrating the skin. CD30+ T-cell lymphomas present clinically as nodules with a diameter between 1 and 15 cm, mostly in elderly patients.
Georgi Tchernev +3 more
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OX40 Ligand and CD30 Ligand Are Expressed on Adult but Not Neonatal CD4+CD3− Inducer Cells: Evidence That IL-7 Signals Regulate CD30 Ligand but Not OX40 Ligand Expression [PDF]
The Journal of Immunology, 2005 Abstract In this report, we have examined the expression of the T cell survival signals, OX40 ligand (OX40L) and CD30 ligand (CD30L) on CD4+CD3−CD11c−B220−IL-7Rα+ inducer cells from birth to adulthood in mice. We found that adult but not neonatal inducer cells expressed high levels of OX40L and CD30L, whereas their expression of TNF ...
Mi-Yeon, Kim +7 more
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BMC Research Notes, 2020 Objective Programmed death-1 (PD-1) and its ligand PD-L1 are now used as predictive biomarkers to guide clinical decisions. Precise characterization of PD-L1-positive cells may contribute to our knowledge of which patients derive benefit from the PD-L1 ...
Markus Tiemann +3 more
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Novel Immunotherapy Options for Extranodal NK/T-Cell Lymphoma
Frontiers in Oncology, 2018 Extranodal NK/T-cell lymphoma (ENKTCL) is a highly aggressive mature NK/T-cell neoplasm marked by NK-cell phenotypic expression of CD3ε and CD56. While the disease is reported worldwide, there is a significant geographic variation with its highest ...
Boyu Hu, Yasuhiro Oki
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