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Unveiling the role of angiogenesis-related biomarkers in diabetic nephropathy via transcriptomics. [PDF]
Diabetol Metab SyndrZhao S, Yang C, Gao L, Fan X, Liu S.
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Targeting Lung Cancer Cell Motility Using Microbeam Radiation Therapy. [PDF]
CellsDağkazanlı Ö +6 more
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The role of CD44 in pathological angiogenesis
The FASEB Journal, 2020Angiogenesis is required for normal development and occurs as a pathological step in a variety of disease settings, such as cancer, ocular diseases, and ischemia.
Li Chen +5 more
semanticscholar +1 more source
Critical Reviews in Clinical Laboratory Sciences, 2002
CD44 is a multistructural and multifunctional cell surface molecule involved in cell proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines, chemokines, and growth factors to the corresponding receptors, and docking of proteases at the cell membrane, as well as in signaling for cell survival.
David, Naor +4 more
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CD44 is a multistructural and multifunctional cell surface molecule involved in cell proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines, chemokines, and growth factors to the corresponding receptors, and docking of proteases at the cell membrane, as well as in signaling for cell survival.
David, Naor +4 more
openaire +2 more sources
Evaluating the Efficiency of Hyaluronic Acid for Tumor Targeting via CD44.
Molecular Pharmaceutics, 2019The development of delivery systems capable of tumor targeting represents a promising strategy to overcome issues related to nonspecific effects of conventional anticancer therapies.
A. Spadea +7 more
semanticscholar +1 more source
European Journal of Cancer, 1995
Alternative splicing of ten different variant exons (v1-v10) is responsible for the creation of a large number of different CD44 surface proteins. Some of these proteins play decisive roles in the metastatic spread of rat tumours. Also in human cancers, CD44 splice variants are frequently expressed in advanced states of tumorigenesis.
Herrlich, P., Pals, S. T., Ponta, H.
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Alternative splicing of ten different variant exons (v1-v10) is responsible for the creation of a large number of different CD44 surface proteins. Some of these proteins play decisive roles in the metastatic spread of rat tumours. Also in human cancers, CD44 splice variants are frequently expressed in advanced states of tumorigenesis.
Herrlich, P., Pals, S. T., Ponta, H.
openaire +2 more sources
Breast Disease, 2019
Breast cancer (BC) is among the most prevalent type of malignancy affecting females worldwide. BC is classified into different types according to the status of the expression of receptors such as estrogen receptor (ER), human epidermal growth factor ...
Nihad Al-Othman +5 more
semanticscholar +1 more source
Breast cancer (BC) is among the most prevalent type of malignancy affecting females worldwide. BC is classified into different types according to the status of the expression of receptors such as estrogen receptor (ER), human epidermal growth factor ...
Nihad Al-Othman +5 more
semanticscholar +1 more source
ACS Applied Materials and Interfaces, 2019
The serum level of soluble CD44 is directly associated with several clinicopathological parameters of malignant diseases. There is a great need for the development of an easy and cost-effective detection method for soluble CD44 for both the diagnosis and
Bobo Fan +6 more
semanticscholar +1 more source
The serum level of soluble CD44 is directly associated with several clinicopathological parameters of malignant diseases. There is a great need for the development of an easy and cost-effective detection method for soluble CD44 for both the diagnosis and
Bobo Fan +6 more
semanticscholar +1 more source
Frontiers in Bioscience, 1998
In this review we discuss the structural elements of CD44 that have been shown to be involved in specific functions. To this end, we focus primarily on experiments in which CD44 constructs are transfected into cells whose function is then assayed. The hyaluronan binding function of CD44 has been assayed in cell lines and in fusion proteins, termed CD44-
J, Lesley, R, Hyman
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In this review we discuss the structural elements of CD44 that have been shown to be involved in specific functions. To this end, we focus primarily on experiments in which CD44 constructs are transfected into cells whose function is then assayed. The hyaluronan binding function of CD44 has been assayed in cell lines and in fusion proteins, termed CD44-
J, Lesley, R, Hyman
openaire +2 more sources