Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
Mitochondrial Abnormalities of T Lymphocytes in Patients With Maintenance Hemodialysis. [PDF]
Luo C +6 more
europepmc +1 more source
The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng +10 more
wiley +1 more source
First report on leucocytes cell population data as an applicable test for clinical stratification in people living with HIV. [PDF]
Ramadan HK +8 more
europepmc +1 more source
The Relationship Between Vascular Endothelial Growth Factor Expression in T Cell Subsets and Survival of Patients With Colorectal Cancer. [PDF]
Artaç M +7 more
europepmc +1 more source
Comparison of Tissue Preparations to Identify and Phenotype T Cells in Human Colorectal Tumor Tissue
ABSTRACT Archived patient samples (e.g., formalin‐fixed paraffin embedded (FFPE) tissue blocks, cryoembedded tissue blocks, and frozen whole tissue samples) are a source of immune information for which corresponding patient data is often collected.
Justin F. Tirados +5 more
wiley +1 more source
Rebooting immunity in congenital athymia: Factors impacting reconstitution with thymus implantation. [PDF]
Cresoe-Ortiz S +7 more
europepmc +1 more source
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley +1 more source
Specific Deficiency of Naïve CD4+ T Lymphocytes Characterizes Heart Failure and Heightens Mortality Risk in the HRS. [PDF]
Zidar DA +15 more
europepmc +1 more source
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley +1 more source

