Results 231 to 240 of about 98,906 (300)

Seroepidemiology and Reactivation Rates of Cytomegalovirus in HIV-Positive Patients in Istanbul: A Retrospective Analysis. [PDF]

Viruses
Sevimli Saydan D, Kir MH, Köksal MO, Sarsar K, Hulikyan A, Cagatay A, Demirci M, Soguksu P, Yurtseven E, Akkoyunlu SZ, Meşe S, Agacfidan A, Kirkoyun Uysal H.   +12 more
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Relationship Between Onychomycosis and HIV: A Systematic Review. [PDF]

J Fungi (Basel)
Cruz-López S, Albavera-Ramírez EA, Arenas R, Fuentes-Venado CE, Calzada-Mendoza CC, Farfán-García ED, Castillo-Cruz J, Chávez-Gutiérrez E, Martínez-Herrera E, Pinto-Almazán R.   +9 more
europepmc   +1 more source

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

iMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou, Zishuai Wang, Chenghao Hu, Shuhan Deng, Changyun Cai, Yanfang Wang, Shang‐Tong Li, Lijing Bai, Kui Li   +8 more
wiley   +1 more source

Immunological impact of age and comorbidities: findings from the REALISM and SENIOR-HLA-DR cohorts. [PDF]

Aging Clin Exp Res
Vieilledent L, Gaujard S, Gossez M, Broyer A, Bodinier M, Goff SL, Di-Valentin K, Renaud E, Dumay C, Foray AP, Monneret G, Venet F.   +11 more
europepmc   +1 more source

Metal‐dependent regulated cell death: Molecular architecture and translational frontiers

iMeta, EarlyView.
Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu, Zhe Chen, Yaqi Li, Jiayi Peng, Jiangang Cao, Hong Zhou, Mengqi Wang, Yuejia Du, Hailin Wu, Huiqin Zhao, Shifang Huang, Dianmei Yu, Meiqing Liu, Olga V. Shevchenko, Natalia Yu. Matveeva, Yiyuan Yang, Kerui Huang, Deguan Lv, Junxia Min, Linxi Chen, Fudi Wang   +20 more
wiley   +1 more source

The exploration of immune system function changes in marathon athletes after high-intensity training by Agent-Based Model. [PDF]

Front Sports Act Living
Tian H, Zuo R, Wang D, Qian G, Ye Q, Kawczyński A, Trybulski R, Clemente FM.   +7 more
europepmc   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source

A Novel Variant of CORO1A Gene Contributing to the Development of Primary Immunodeficiency in Children. [PDF]

Case Reports Immunol
Aljohani A, Alayed Y, Alrasheed B, Alghamdi H, Alzahrani M, Alshaigi K.   +5 more
europepmc   +1 more source