Results 191 to 200 of about 49,530 (262)

Low Dose of IL‐2 Application for Graft‐Versus‐Host Disease Prophylaxis Following Haploidentical Stem Cell Transplantation

MedComm, Volume 7, Issue 2, February 2026.
Early low‐dose IL‐2 administration after haploidentical HSCT promotes the reconstitution of NK cells and regulatory T cells (Tregs), enhances their activation (CD122+, DNAM‐1+, NKG2D+, CD62L+), and increases plasma cytokines (IFN‐γ, TNF‐α, IL‐10, IL‐2).
Zheng‐Li Xu, Meng Lv, Xing‐Xing Yu, Yi‐Yang Ding, Ting‐Ting Han, Hai‐Xia Fu, Yuan‐Yuan Zhang, Xiao‐Dong Mo, Yu‐Qian Sun, Lan‐Ping Xu, Xiao‐Hui Zhang, Yu Wang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source

Nanobiotechnology‐Based Approaches for Uveal Melanoma Treatment

SmartMat, Volume 7, Issue 1, February 2026.
Emerging platforms for uveal melanoma combine precision drug delivery, ROS‐amplifying modalities, and nucleic acid transport to overcome ocular barriers and immunosuppressive niches. Targeted nanoparticles, virus‐like constructs, and injectable depots enable localized activation, controlled release, and gene‐level reprogramming.
Nadezhda A. Pechnikova, Ioannis Iliadis, Malamati Poimenidou, Chrysi Patsidou, Maria Zafeiriou‐Chatziefraimidou, Diamantis D. Almaliotis, Ioannis T. Tsinopoulos, Ivan V. Zelepukin, Alexey V. Yaremenko   +8 more
wiley   +1 more source

Causal Relationship between Immune Cells and Postpartum Depression: A Bidirectional Two-Sample Mendelian Randomization Study. [PDF]

Iran J Public Health
Zhu Y, Cheng F, Wang W, Yang X, He M, Zhang Z, Zhu L.   +6 more
europepmc   +1 more source

Hepatic CD4 T Cells Predict Hepatocellular Carcinoma Risk on Metabolic Dysfunction‐Associated Steatohepatitis Patients

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background & Aims Metabolic dysfunction‐associated steatohepatitis (MASH) increasingly drives hepatocellular carcinoma (HCC) development. We characterized inflammatory infiltrates in liver biopsies from MASH patients who developed HCC versus controls to identify predictive immune signatures. Method Formalin‐fixed paraffin‐embedded (FFPE) liver
Emilse Rodriguez, Peter Simon, Sabrina Dhooge, Marina Fernandez, Patricia Calafat, María Kurpis, Nicolás Nuñez, Jhon Prieto, Anna Saborowski, Arndt Vogel, José Daniel Debes, Domingo Cesar Balderramo, Andre Boonstra, Pablo Alberto Romagnoli   +13 more
wiley   +1 more source

Three neutrophilic granulocyte's subpopulations CD62L (dim+)CD63(dim+), CD62L (bright+)CD63(dim+) and CD62L (dim+)CD63(mid+) in newborns with congenital pneumonia

, 2020
Nesterova I.V., Chudilova G.A., Lomtatidze L.V., Kleschenko E., Kovaleva S., Smerchinskaj T., Sapun O.   +6 more
openaire   +1 more source

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

Allergy, Volume 81, Issue 2, Page 498-512, February 2026.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek, Andrea Deinzer, Roman G. Gerlach, Jana Petzold, Lea Semmler, Christof Vorsatz, Padraic G. Fallon, Christian Schwartz   +7 more
wiley   +1 more source

Liraglutide prevents lupus-associated diffuse alveolar hemorrhage via inhibiting lymphocyte infiltration and promoting macrophage M2 polarization. [PDF]

J Transl Autoimmun
Jiang L, He L, Li D, Luo X, Yang M, Wu H, Long H.   +6 more
europepmc   +1 more source

Expression of CD38 on resting peripheral iNKT cells defines an immature subpopulation with distinct functionality in humans

Immunology &Cell Biology, Volume 104, Issue 2, Page 109-124, February 2026.
In this study, we characterize a distinct subpopulation of undifferentiated invariant natural killer T (iNKT) cells in the peripheral blood of healthy adults, which are characterized by CD38 expression in a resting state. This CD38+ subset closely resembles iNKT cells from cord blood and thymus, exhibiting a unique cytokine profile and alterations in ...
Christopher Menne, Naeimeh Tavakolinia, Louis Perriman, Wiebke Moskorz, Christine Cosmovici, Andreas Walker, Lara Olejnik, Katharina Raba, Mei RM Du, Fernando J Rossello, Igor E Konstantinov, Stuart P Berzins, Daniel G Pellicci, Jörg Timm   +13 more
wiley   +1 more source

Correlation of immune cell subsets in the tumor microenvironment and peripheral blood with immunotherapy response in esophageal squamous cell carcinoma. [PDF]

Front Immunol
Chen W, Gong L, Li Y, Wu M, Tao M.
europepmc   +1 more source

LAG‐3+ Regulatory T Cells Suppress Effector Function of T Cells and Allow Their Proliferation Into Regulatory T Cells

Immunology, Volume 177, Issue 2, Page 317-328, February 2026.
LAG‐3+ regulatory T cells suppress the effector but not the proliferative response of naïve cognate antigen‐specific CD4+ T cells in vivo. The suppressed T cells display upregulation of immune checkpoints and downregulation of pro‐inflammatory pathways with enhanced TCR signaling and reduced oxidative metabolism.
Avijit Dutta, Shi‐Chuen Miaw, Tse‐Ching Chen, Chia‐Shiang Chang, Yu‐Lin Huang, Yung‐Chang Lin, Chun‐Yen Lin, Ching‐Tai Huang   +7 more
wiley   +1 more source