Results 31 to 40 of about 49,530 (262)

Intermediate Monocytes with PD-L1 and CD62L Expression as a Possible Player in Active SARS-CoV-2 Infection

Viruses, 2022
Monocytes play a role in viral biology, but little is known about the monocyte subpopulation in the course of COVID-19 disease. The aim of the study was the analysis of classical, intermediate and non-classical monocytes with expression of PD-L1 and ...
Elżbieta Rutkowska, Iwona Kwiecień, Krzysztof Kłos, Piotr Rzepecki, Andrzej Chciałowski   +4 more
doaj   +1 more source

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria [PDF]

, 2015
BACKGROUND Sporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine (CPS-CQ) efficiently induces sterile protection against malaria.
Bijker, Else M, Cockburn, Ian, Nganou-Makamdop, Krystelle, Sauerwein, Robert W, van Gemert, Geert-Jan, Zavala, Fidel   +5 more
core   +2 more sources

Primed tumor-reactive multifunctional CD62L+ human CD8+ T cells for immunotherapy [PDF]

Cancer Immunology, Immunotherapy, 2010
T cell-mediated immunotherapy against malignancies has been shown to be effective for certain types of cancer. However, ex vivo expansion of tumor-reactive T cells has been hindered by the low precursor frequency of such cells, often requiring multiple rounds of stimulation, resulting in full differentiation, loss of homing receptors and potential ...
Matthias, Wölfl, Katharina, Merker, Henner, Morbach, Stefaan W, Van Gool, Matthias, Eyrich, Philip D, Greenberg, Paul G, Schlegel   +6 more
openaire   +2 more sources

Correlation between circulating CD4+CD45RA+CD62L+ T cells and prognosis of metastatic non-small cell lung cancer treated with EGFR-TKI [PDF]

Jichu yixue yu linchuang
Objective To explore the correlation between circulating lymphocyte profiles and the outcomes of non-small cell lung cancer (NSCLC) patients undergoing epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) therapy.
CAO Chenxin, TANG Hui, GENG Ruixuan, GUO Fuping, BAI Chunmei, WANG Yingyi, LI Taisheng
doaj   +1 more source

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +3 more sources

CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo [PDF]

Journal of Clinical Investigation, 2016
Vα24-invariant natural killer T cells (NKTs) localize to tumors and have inherent antitumor properties, making them attractive chimeric antigen receptor (CAR) carriers for redirected cancer immunotherapy. However, clinical application of CAR-NKTs has been impeded, as mechanisms responsible for NKT expansion and the in vivo persistence of these cells ...
Gengwen, Tian, Amy N, Courtney, Bipulendu, Jena, Andras, Heczey, Daofeng, Liu, Ekaterina, Marinova, Linjie, Guo, Xin, Xu, Hiroki, Torikai, Qianxing, Mo, Gianpietro, Dotti, Laurence J, Cooper, Leonid S, Metelitsa   +12 more
openaire   +2 more sources

T cells regulation modulated by Sambucus javanica extracts in DMBA-exposed mice [PDF]

Journal of HerbMed Pharmacology, 2020
Introduction: Sambucus is a genus of the Adoxaceae family and has been widely used as a food and medicinal source. In this study, we aimed to evaluate the effects of S.
Wira Eka Putra, A. Rofiqi Maulana, Arfan Tri Kusuma Ramadhan, Muhaimin Rifa’i   +3 more
doaj   +1 more source

Adenovirus vector-specific T cells demonstrate a unique memory phenotype with high proliferative potential and coexpression of CCR5 and integrin α\(_4\)β\(_7\) [PDF]

, 2009
Background: The Step Study was a randomized trial to reduce HIV infection through vaccination with an adenovirus type 5-based gag/pol/nef construct; analysis following early cessation of the trial revealed an excess of HIV seroconversion in Ad5 ...
Chakupurakal, Geothy, Cobbold, Mark, Mautner, Vivien, Moss, Paul AH, Onion, David   +4 more
core   +1 more source

T Cell Response in Patients with Implanted Biological and Mechanical Prosthetic Heart Valves

Mediators of Inflammation, 2016
The study was aimed at assessing T cell subsets of peripheral blood from recipients of long-term functioning (more than 60 months) biological and mechanical heart valve prostheses.
L. Barbarash, I. Kudryavtsev, N. Rutkovskaya, A. Golovkin   +3 more
doaj   +1 more source

MULTICOLOR FLOW CYTOMETRIC ANALYSIS OF CYTOTOXIC T CELL SUBSETS

Медицинская иммунология, 2016
Multiparameteric flow analysis has offered an ability of simultaneous analysis of multiple molecules at the single-cell level. Peripheral blood cells from 110 healthy subjects aged 18-65 years (59 males and 51 females) were stained with antibodies to CD3,
I. V. Kudryavtsev, A. G. Borisov, I. I. Krobinets, A. A. Savchenko, M. K. Serebryakova   +4 more
doaj   +1 more source