Results 271 to 280 of about 95,816 (289)

CD68: Potential Contributor to Inflammation and RPE Cell Dystrophy

2023
Age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly in developed countries. It is a complex, multifactorial, progressive disease with diverse molecular pathways, including inflammation, regulating its pathogenesis.
Mayur, Choudhary, Goldis, Malek
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CD68 and CR3/43 Immunohistochemical Expression in Secretory Meningiomas

Neurosurgery, 2005
Secretory meningiomas (SMs) are unusual benign meningiomas. SMs are highly vascularized lesions, with angiomatous features and a perivascular arrangement, and they are accompanied frequently by massive peritumoral edema. Microglia have been called the brain's immune system, although the specific role and prognostic significance of microglia remain ...
CAFFO, Maria, CARUSO G, GERMANO', Antonino Francesco, GALATIOTO, Salvatore, MELI F, TOMASELLO, Francesco   +5 more
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CD68 expression in aortocoronary saphenous vein bypass grafts

Histochemistry and Cell Biology, 2012
Atherosclerosis commonly affects the arteries harvested from patients 70 years of age or older. Saphenous vein grafts appear to maintain a higher patency rate after coronary artery bypass grafting in these subjects. The infiltration of macrophages is an early step in saphenous vein graft atherosclerosis; however, little is known regarding the ...
Agnieszka, Malinska, Bartlomiej, Perek, Piotr, Buczkowski, Katarzyna, Kowalska, Danuta, Ostalska-Nowicka, Wojciech, Witkiewicz, Michal, Nowicki   +6 more
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Distribution of the CD68 macrophagr/myeloid associated antigen

International Immunology, 1990
The distribution of the pan-macrophage CD68 antigen, recognized by six different monoclonal antibodies, was examined in human blood, tissue, and cell lines using APAAP staining and Western blotting. All antibodies stained monocytes and macrophages, but labelling of neutrophils, basophils, and lymphocytes was seen with some of the reagents. In addition,
K A, Pulford, A, Sipos, J L, Cordell, W P, Stross, D Y, Mason   +4 more
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CD68+ Reactive histiocytosis complicating early gastric cancer

Pathology International, 1995
A peculiar form of reactive, non‐granulomatous proliferation of CD68+ histiocytes was demonstrated, for the first time, in the submucosal layer just beneath the IIa‐type early gastric adenocarcinoma that focally invaded submucosal lymphatics. The histiocytic cells possessed plump eosino‐philic and often foamy cytoplasm and eccentric small nuclei with ...
Yukari Ogawa, Ken‐ichi Inada, Yutaka Tsutsumi   +2 more
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Expression of the CD68 glycoprotein in the rat epididymis

Biochimie, 2015
The 110 kDa trans-membrane glycoprotein CD68 is highly expressed by human monocytes and tissue macrophages. However, in addition to the monocyte/macrophage system, CD68 has been also found in normal and tumor cells with no macrophagic activity such as lymphocytes, fibroblasts, endothelial cells, small intestinal epithelial cells, and neoplastic cells ...
LIGUORI, GIOVANNA, DE PASQUALE, VALERIA, DELLA MORTE, ROSSELLA, AVALLONE, LUIGI, COSTAGLIOLA, ANNA, VITTORIA, ALFREDO, TAFURI, SIMONA   +6 more
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Clinicopathological significance of tubulointerstitial CD68 macrophages in proliferative lupus nephritis

Clinical Rheumatology, 2022
Tubulointerstitial macrophage plays a pathogenic role in renal damage of lupus nephritis (LN). However, the clinical and pathological role of these CD68 macrophages has not been fully described. The aim of the present study is to decipher the correlation between clinicopathological features and tubulointerstitial CD68 macrophages in 76 proliferative LN
Jiejian Chen, Linlin Cui, Jinge Ouyang, Jian Wang, Weijia Xu   +4 more
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[Epitope analysis of CD68 antigens].

Allergie und Immunologie, 1992
Different epitopes of CD68 antigen are detectable by three new generated monoclonal antibodies (MABs) BL-M68/1-3 (all mouse IgM). The MAB BL-M68/3 reacts with an epitope, which is stable also in formalin-fixed paraffin-embedded tissues. In immunohistochemical blocking experiments using the own biotinylated MABs and six CD68 MABs from the IV.
D, Ulsijchutagijn, H, Kupper, W, Eichler, H, Fiebig   +3 more
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Cyclophilin a increases CD68+ cell infiltration in rat experimental periodontitis

Journal of Molecular Histology, 2018
Cyclophilin A (CyPA) is a potent chemokine, which can directly induce leukocyte chemotaxis and contribute to the pathogenesis of inflammation-mediated diseases. This study is to observe the expression and distribution of CyPA and CD68+ cells in the histopathogenesis of rat ligation-induced experimental periodontitis, and assess the role of CyPA in CD68+
Lande Xue, Linwang Su, Li Zhao, Jianxia Li, Yi Du, Xijiao Yu   +5 more
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T lymphocytes, CD68-positive cells and vascularisation in thyroid carcinomas

Journal of Cancer Research and Clinical Oncology, 1994
Immunohistochemical detection and quantification of CD3- and CD45RO-positive lymphocytes and CD68-positive cells in 75 thyroid carcinomas of follicular cell origin revealed rising levels for these parameters associated with dedifferentiation. A parallel trend towards reduction of vascularisation, determined as CD31-positive blood vessels, with ...
G, Herrmann, P M, Schumm-Draeger, C, Müller, E, Atai, B, Wenzel, T, Fabian, K H, Usadel, K, Hübner   +7 more
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