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Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection. [PDF]

open access: yesGut
Preechanukul A   +20 more
europepmc   +1 more source

Proteasome alteration between epithelial and hematopoietic cells facilitates positive selection of CD8 T cells. [PDF]

open access: yesNat Commun
Matsuda-Lennikov M   +14 more
europepmc   +1 more source
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Antimetastatic defense by CD8+ T cells

Trends in Cancer, 2022
Metastasis is an intricate process whereby tumor cells migrate from the primary tumor, survive in the circulation, seed distal organs, and proliferate to create metastatic foci. CD8+ T cells can detect and eliminate tumor cells. Research on CD8+ T cell–dependent antitumor immunity has classically focused on its role in the primary tumor.
Tallón de Lara, Paulino   +3 more
openaire   +2 more sources

CD8 T cells are forever

Science Immunology, 2023
Iterative acute stimulations can maintain CD8 T cells for longer than their organismal lifespan.
openaire   +2 more sources

CD8+ T cells in autoimmunity

Current Opinion in Immunology, 2005
Mounting evidence shows that CD8(+) T cells contribute to the initiation, progression and regulation of several pathogenic autoimmune responses in which these cells were not previously thought to play a major role. CD8(+) T cells can kill target cells directly, by recognizing peptide-MHC complexes on target cells, or indirectly, by secreting cytokines ...
Ulrich, Walter, Pere, Santamaria
openaire   +2 more sources

CD8+ T Cells in Tuberculosis

American Journal of Respiratory and Critical Care Medicine, 2002
This chapter focuses on CD8 T cells, with an emphasis on the major histocompatibility complex (MHC) Ia-restricted T cells in tuberculosis, and also touches upon the unconventional CD8 T cells restricted by β2m-associated nonclassical MHC Ib or MHC I-like molecules. Although the T cells which recognize mycobacterial glycolipids in the context of group I
Vanja, Lazarevic, JoAnne, Flynn
openaire   +2 more sources

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