Limited in vitro differentiation of porcine induced pluripotent stem cells into endothelial cells
Background: Pluripotent stem cells (PSCs) including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) offer the immense therapeutic potential in stem cell-based therapy of degenerative disorders.
In-Won Lee +8 more
doaj +1 more source
A Multi-Objective Optimization Framework for Offshore Wind Farm Layouts and Electric Infrastructures
Current offshore wind farms (OWFs) design processes are based on a sequential approach which does not guarantee system optimality because it oversimplifies the problem by discarding important interdependencies between design aspects.
Silvio Rodrigues +6 more
doaj +1 more source
Die Angiogenese nimmt bei physiologischen Vorgängen des menschlichen Organismus, wie der plazentäre und embryonale Entwicklung, der Gewebsneubildung und Gewebsreparatur eine wichtige Stellung ein, spielt aber auch bei der Entstehung von Krankheiten, insbesondere bei der Entwicklung von malignen Tumoren und deren Metastasierung eine Rolle. Tumorwachstum
Buch, Thomas +1 more
openaire +3 more sources
Inflammatory cytokines have been shown to mediate organ damage by their action on vascular endothelia and leukocytes, in part by upregulating the expression of adhesion molecules, which in turn convey transmigration of leukocytes into tissue. The upregulation and activation of vascular cell adhesion molecules on the endothelial cells avail firm ...
Kleinhans, Helge +8 more
openaire +3 more sources
A new stable phosphorus ylide (p-tolyl)(3)P = CHCOC6H4(p-CN) (Y) was synthesized and a series of novel complexes based on metalated phosphorus ylides were prepared through the reaction of (p-tolyl)(3)P = CHCOC6H4(p-CN) with mercury(II) halides, AgNO3 and
Bayat, Mehdi +5 more
core +1 more source
Gliadin peptides induce tissue transglutaminase activation and ER-stress through Ca2+ mobilization in Caco-2 cells. [PDF]
BACKGROUND: Celiac disease (CD) is an intestinal inflammatory condition that develops in genetically susceptible individuals after exposure to dietary wheat gliadin.
Ivana Caputo +6 more
doaj +1 more source
Ab-initio calculation of the ${}^6Li$ binding energy with the Hybrid Multideterminant scheme
We perform an ab-initio calculation for the binding energy of ${}^6Li$ using the CD-Bonn 2000 NN potential renormalized with the Lee-Suzuki method. The many-body approach to the problem is the Hybrid Multideterminant method.
A.F. Lisetskiy +33 more
core +1 more source
Multivariate Techniques for Identifying Diffractive Interactions at the LHC [PDF]
31 pages, 14 figures, 11 tablesClose to one half of the LHC events are expected to be due to elastic or inelastic diffractive scattering. Still, predictions based on extrapolations of experimental data at lower energies differ by large factors in ...
Kuusela, Mikael +4 more
core +2 more sources
The clinical and phenotypical assessment of seronegative villous atrophy; a prospective UK centre experience evaluating 200 adult cases over a 15-year period (2000-2015). [PDF]
BACKGROUND: Seronegative villous atrophy (SNVA) is commonly attributed to coeliac disease (CD). However, there are other causes of SNVA. More recently angiotensin-2-receptor-blockers (A2RBs) have been reported as an association but data on SNVA have been
Aziz, I. +9 more
core +1 more source
Ten-year observation of corneal densitometry and associated factors following small incision lenticule extraction [PDF]
AIM: To investigate the long-term changes of corneal densitometry (CD) and its contributing elements after small incision lenticule extraction (SMILE). METHODS: Totally 31 eyes of 31 patients with mean spherical equivalent of -6.46±1.50 D and mean age 28.
Xiao-Song Han +6 more
doaj +1 more source

