Results 71 to 80 of about 2,409,440 (275)

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Glycyrrhiza Extract and Curcumin Alleviates the Toxicity of Cadmium via Improving the Antioxidant and Immune Functions of Black Goats

Toxics
To investigate the mitigative effects of glycyrrhiza extract (GE) and curcumin (CUR) on the antioxidant and immune functions of the Guizhou black goat exposed to cadmium (Cd), 50 healthy Guizhou black goats (11.08 ± 0.22 kg, male, six months old) were ...
Yang Ran, Xiaoyun Shen, Yuanfeng Li
doaj   +1 more source

Expression and significance of cell immunohistochemical markers (HHF-35, CD-31, Bcl-2, P-53 and apopDETEC) in hypertrophic cardiomyopathy.

Histology and histopathology, 2004
There are several hypotheses concerning the pathogenesis of hypertrophic cardiomyopathy (genetic, ischaemic, immune, inflammatory and apoptosis induction). We have studied three types of cardiomyopathy in order to observe the expression and assess the significance of different immunohistochemical markers (muscular actin, CD-31, proliferation cell ...
Martínez Díaz, F., Bernal-Gilar, M., Gómez Zapata., Maximiliano, Luna, A.   +3 more
openaire   +3 more sources

Bioluminescence Imaging of Angiogenesis in a Murine Orthotopic Pancreatic Cancer Model [PDF]

, 2018
Purpose: Angiogenesis is essential for physiological processes as well as for carcinogenesis. New approaches to cancer therapy include targeting angiogenesis. One target is VEGF-A and its receptor VEGFR2.
Angst, Eliane, Chen, Monica, Eibl, Guido, Hines, O., Mojadidi, Michelle, Reber, Howard   +5 more
core  

Evolution of costs of inflammatory bowel disease over two years of follow-up [PDF]

, 2016
Background: With the increasing use of anti-TNF therapy in inflammatory bowel disease (IBD), a shift of costs has been observed with medication costs replacing hospitalization and surgery as major cost driver.
Bodegraven, A.A. (Ad) van, Bolwerk, C.L. (Clemens), Clemens, P.R. (Paula ), De Jong, D.J. (Dirk J.), Dijkstra, G. (Gerard), Fidder, M. (Melissa), Have, M. (Mike) van der, Jansen, J.M. (Jeroen Michiel), Leenders, M. (Max), Mahmmod, N. (Nofel), Mangen, M.J.J., Meeberg, P.C. (Paul) van de, Meulen-de Jong, A.E. (Andrea) van der, Oldenburg, B. (Bas), Ponsioen, C.Y. (Cyril), Romberg-Camps, M. (Mariëlle), Severs, M., Siersema, P.D. (Peter), Valk, M.E. (Mirthe) van der, Vermeijden, J.R. (J. Reinoud), Woude, C.J. (Janneke) van der   +20 more
core   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Controlling the Melt Resistance to Flow as a Possibility of Improving the Miscibility and the Time Behavior of Some Blends Based on Starch

International Journal of Polymer Science, 2015
The paper proves that the miscibility of some blends based on starch can be improved by finding for each of them the melt resistance to flow at which the nonstationary flow and the melt degradation are avoided and the developed shear rate homogenizes ...
Doina Dimonie, Miruna Musat, Sanda Maria Doncea, Celina Maria Damian, Liliana Anton, Eugeniu Vasile, Roxana Trusca, Maria Râpă   +7 more
doaj   +1 more source

Report of the Third Interlaboratory Comparison Organised by the Community Reference Laboratory for Heavy Metals in Feed and Food - Total Cd, Pb and Hg and Extractable Cd and Pb in Feed [PDF]

, 2008
The Institute for Reference Materials and Measurements (IRMM) of the European Commission's Directorate-General Joint Research Centre holds the Community Reference Laboratory for Heavy Metals in Feed and Food (CRL-HM). One of its core tasks is to organise
BYNENS SASKIA, DE LA CALLE GUNTINAS MARIA BEATRIZ, TAYLOR PHILIP, VAN DE KREEKE JOHANNES, VERBIST INGE   +4 more
core   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source