Results 41 to 50 of about 330,731 (313)

Distinct expression levels of ALS, LIP and SAP genes in Candida tropicalis with diverse virulent activities

Frontiers in Microbiology, 2016
Candia tropicalis is an increasingly important human pathogen, causing nosocomial fungemia among patients with neutropenia or malignancy (Guinea, 2014). However, limited research has been published concerning its pathogenicity. Based on the phenotypes of
Shuanbao Yu, Wenge Li, Xiaoshu Liu, Jie Che, Yuan Wu, Jinxing Lu   +5 more
doaj   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Endonuclease restriction-mediated real-time polymerase chain reaction: a novel technique for rapid, sensitive and quantitative detection of nucleic-acid sequence

Frontiers in Microbiology, 2016
The article reported a novel methodology for real-time PCR analysis of nucleic acids, termed endonuclease restriction-mediated real-time polymerase chain reaction (ET-PCR). Just like PCR, ET-PCR only required one pair of primers.
Yi Wang, Yan Wang, Lu Zhang, Machao Li, Lijuan Luo, Liu Dongxin, Hua Li, Xiaolong Cao, Xiaolong Cao, Shoukui Hu, Dong Jin, Jianguo Xu, Changyun Ye   +12 more
doaj   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Update on trends in varicella mortality during the varicella vaccine era—United States, 1990–2016

Human Vaccines & Immunotherapeutics, 2018
We reported previously that the annual average mortality rate in the United States in 2008–2011 for varicella listed as the underlying cause declined 87% compared with the prevaccine period (1990–1994).
Jessica Leung, Mona Marin
doaj   +1 more source

Multiplex, rapid and sensitive isothermal detection of nucleic-acid sequence by endonuclease restriction-mediated real-time multiple cross displacement amplification

Frontiers in Microbiology, 2016
We have devised a novel isothermal amplification technology, termed endonuclease restriction-mediated real-time multiple cross displacement amplification (ET-MCDA), which facilitated multiplex, rapid, specific and sensitive detection of nucleic-acid ...
Yi eWang, Yan eWang, Lu eZhang, Dongxin eLiu, Lijuan eLuo, Hua eLi, Xiaolong eCao, Xiaolong eCao, Kai eLiu, Jianguo eXu, Changyun eYe   +10 more
doaj   +1 more source

How CDC foundered

Science, 2020
The agency's missteps were multiplied by political interference.
openaire   +2 more sources

Cavity‐Enhanced Eye‐Readable Detection of 0.1% H2 via Active Modulation of Charge‐Transfer Plasmons

Advanced Science, EarlyView.
A cavity‐structured nanoparticle sensor is developed for highly sensitive, eye‐readable hydrogen detection. Its excellent colorimetric response arises from a hydrogen‐induced charge‐transfer mechanism: reduction of the dielectric oxide shell in H2 triggers a transition from the plasmonic gap mode to the charge‐transfer plasmon mode.
Xuemin Zhang, Shunsheng Ye, Lubing Cai, Chao Li, Zheng Cai, Jin Zhang, Fei Liu, Tieqiang Wang, Boxin Wei, Hongbo Zeng   +9 more
wiley   +1 more source

Os sistemas de classificação bibliográfica como interface biblioteca/usuário

Ciência da Informação, 1996
As classificações refletem o contexto social no qual foram elaboradas. O contexto histórico e social no qual foram criadas tanto a CDD quanto a CDU difere do contexto histórico atual no qual se presencia infovias, redes de computadores, serviços self ...
Maristela Cid Gigante
doaj  

An Interesting Case of Renal Transplantation: Resolving Discrepancies in Histocompatibility Testing

Indian Journal of Transplantation
Histocompatibility testing plays an important role in the success of renal transplantation outcome by ensuring optimal donor recipient compatibility. Developments in testing methods have increased transplant success, but discrepancies between different ...
Vikash Chandra Mishra, Dinesh Chandra, Ritu Sharma, Vimarsh Raina   +3 more
doaj   +1 more source