Results 61 to 70 of about 330,731 (313)

Cyclic distraction–compression promotes bone regeneration during distraction osteogenesis through the Piezo1–YAP–β-catenin axis

open access: yesFrontiers in Bioengineering and Biotechnology
BackgroundDistraction osteogenesis (DO) is an effective reconstructive strategy for large bone defects, but its clinical application is constrained by slow regenerate maturation and prolonged consolidation.
Lian Tang   +24 more
doaj   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

open access: yesAdvanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang   +13 more
wiley   +1 more source

Value of implementing a care bundle approach to improve outcome of pediatric ventilator − associated events (PedVAE) in pediatric intensive care unit (PICU)

open access: yesInternational Journal of Pediatrics & Adolescent Medicine
Background Pediatric ventilator-associated events (PedVAEs) refer to a persistent deterioration in oxygenation following a period of stability, and these are valuable for monitoring and detecting issues arising from mechanical ventilation in children ...
Nagwa Mohamed Sabry Mahmoud   +3 more
doaj   +1 more source

A test method for evaluating the thermal environment of underground coal mine refuge alternatives

open access: yesInternational Journal of Mining Science and Technology, 2019
Since 2009, the Mine Safety and Health Administration (MSHA) has required mines to install refuge alternatives (RAs) in underground coal mines. One of the biggest concerns with occupied RAs is the possible severity of the resulting thermal environment ...
D.S. Yantek   +4 more
doaj   +1 more source

Receptor‐Triggered Peptide Self‐Assembly Enables Multivalent Recruitment of Endogenous Antibodies for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Receptor‐triggered supramolecular self‐assembly converts monovalent antibody‐recruiting molecules into multivalent platforms directly on cancer cell membranes. The resulting fibrillar assemblies present clustered haptens that efficiently recruit endogenous antibodies, enabling selective complement‐mediated immune killing of EGFR‐positive cancer cells ...
Yihui Wang   +6 more
wiley   +1 more source

Evaluación de la respuesta hidrológica del modelo DWB en la curva de duración de caudales a nivel de cuenca y microcuenca, caso de estudio la cuenca del río Sogamoso, Colombia

open access: yesTecnología y ciencias del agua
Las curvas de duración de caudales (CDC) reflejan los efectos de las características de una cuenca sobre los caudales, esto sin tener en cuenta la temporalidad de ocurrencia.
Camila García-Echeverri   +4 more
doaj   +1 more source

Intermittent Fasting Reduces Taurine Availability and Promotes Antitumor Immunity Through PERK Attenuation‐Associated Paraptosis‐Like Cell Death in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies reduced taurine availability as a mediator of intermittent fasting in colorectal cancer and shows that taurine interacts with GRP78 to maintain PERK abundance post‐transcriptionally. It further shows that taurine depletion destabilizes PERK, induces immunogenic paraptosis, remodels the tumor microenvironment toward a CD8+ T cell ...
Baohui Song   +11 more
wiley   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

open access: yesAdvanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu   +12 more
wiley   +1 more source

CMV on surfaces in homes with young children: results of PCR and viral culture testing

open access: yesBMC Infectious Diseases, 2018
Background Caring for young children is a known risk factor for cytomegalovirus (CMV) infection mainly through exposure to their saliva and urine. In a previous study, 36 CMV-seropositive children 2 mo. to 4 years old were categorized as CMV shedders (n =
Minal M. Amin   +6 more
doaj   +1 more source

Low‐Field Giant Dielectric Tunability by Polaron‐Mediated Interfacial Polarization in Pulsed‐Laser‐Deposited‐Nanocrystalline/Amorphous Composite BaTiO3 Thin Films

open access: yesAdvanced Electronic Materials, EarlyView.
Comparison of tunability efficiency between vacuum‐deposited PLD‐BTO films grown at Td = 550°C in the present study and representative previous reports. ABSTRACT Electrically tunable dielectric thin films are essential components for next‐generation low‐voltage electronic devices.
Shinya Kondo   +7 more
wiley   +1 more source

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