Results 121 to 130 of about 38,210 (217)
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the worldwide leading cause of liver‐related mortality with a prevalence of 75% among individuals with obesity and lacking screenings tools. Extracellular vesicles (EVs)‐based microRNAs (miRNAs) have emerged as promising biomarkers with important roles in the pathogenesis of ...
Katja Lund Cliff +7 more
wiley +1 more source
ABSTRACT Influenza viruses cause seasonal epidemics, and current vaccines do not fully protect against them. This study focuses on long non‐coding RNAs (lncRNAs), which are RNA molecules that do not code for proteins but play crucial roles in various biological processes. We identified 17 lncRNAs altered by the influenza virus.
Samuel Pushparaj +9 more
wiley +1 more source
Metabolic Regulation of Macrophages in Health and Disease
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
wiley +1 more source
AP‐1B Controls Several Levels of Cell Proliferation and Differentiation in Mouse Enteroids
We show that in mouse intestinal organoids, AP‐1B is implicated in apical polarity, differentiation in the secretory lineage and proliferation. In particular, we propose that proliferation is controlled by AP‐1B via the mTOR and YAP pathways. Arrows show the functional links that were elucidated in this study, and dotted lines show putative downstream ...
Maela Duclos +5 more
wiley +1 more source
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia +7 more
wiley +1 more source
ABSTRACT Background GLP‐1 receptor agonists (GLP‐1 RAs) can induce rapid weight reduction, often associated with facial volume loss. However, optimal regenerative strategies remain unclear. Aims To compare the mechanotransduction profiles of the major injectable collagen biostimulator classes in GLP‐1 RA–induced facial aging.
Chang‐Hwan Cho +2 more
wiley +1 more source
Correction: Cdc42 interacts with chaperone Ydj1 to enhance its stability and partitioning during asymmetric cell division and aging in yeast. [PDF]
PLOS Biology Staff.
europepmc +1 more source
Implications of Rho GTPase signaling in cancer immunotherapy. [PDF]
Cai M, Guo F, Zheng Y.
europepmc +1 more source
Prognostic Significance of Cdc42 Expression in Colorectal Cancer and Its Concordance Between Primary Tumors and Matched Metastases: A Retrospective Observational Study. [PDF]
Aktepe OH +4 more
europepmc +1 more source

