Results 81 to 90 of about 37,980 (212)
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba +4 more
wiley +1 more source
FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones. [PDF]
PLoS ONE, 2016 Netrin-1 is an essential extracellular chemoattractant that signals through its receptor DCC to guide commissural axon extension in the embryonic spinal cord.
Benjamin Rappaz +4 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta +3 more
wiley +1 more source
Opposing Expressions of Nidogen-1 and Cdc42 Genes in the Development of Liver Cirrhosis in Patients with Non-Alcoholic Fatty Liver Disease [PDF]
پزشکی بالینی ابن سیناBackground and Objective: The roles of Nidogen-1 and Cdc42 genes as significant factors in the metabolism of the extracellular matrix have been demonstrated in the fibrosis of various tissues. This study investigates the gene expressions of Nidogen-1 and
Zahra Ali +2 more
doaj
Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall
eLife, 2014 Cdc42 is a signaling protein important for reorganization of actin cytoskeleton and morphogenesis of cells. However, the functional role of Cdc42 in synaptic plasticity and in behaviors such as learning and memory are not well understood.
Il Hwan Kim +3 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
The role of Rho GTPases in facial morphogenesis
Developmental Dynamics, EarlyView.The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
Secretopathies emerge as a new class of neurocristopathies
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
wiley +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2019 Xing-Hua Xiao,* Qi-Yuan Huang,* Xian-Ling Qian,* Jing Duan, Xue-Qiao Jiao, Long-Yuan Wu, Qing-Yun Huang, Jun Li, Xing-Ning Lai, Yu-Bo Shi, Li-Xia Xiong Department of Pathophysiology, Medical College, Nanchang University, Nanchang 330006, People’s ...
Xiao XH +10 more
doaj
Spontaneous Cdc42 polarization independent of GDI-mediated extraction and actin-based trafficking.
PLoS Biology, 2015 The small Rho-family GTPase Cdc42 is critical for cell polarization and polarizes spontaneously in absence of upstream spatial cues. Spontaneous polarization is thought to require dynamic Cdc42 recycling through Guanine nucleotide Dissociation Inhibitor (
Felipe O Bendezú +5 more
doaj +1 more source