The adapt-to-nutrient NRPS-like secondary metabolite gene cluster facilitates Verticillium dahliae adaptation to different nutrient environments. [PDF]
Chen YY +7 more
europepmc +1 more source
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
A CD40-targeting peptide, OPT501, modulates inflammation in canine diabetes mellitus improving clinical outcomes. [PDF]
Vaitaitis GM +6 more
europepmc +1 more source
A sulfonated poly(ether ether ketone)‐based hybrid membrane is fabricated with fluorine‐doped carbon dot (FCD) and functionalized metal organic framework (MIL−101−NH2). The novel design reduces unwanted ion crossover while maintaining a sufficient proton transport pathway.
Tan Trung Kien Huynh +8 more
wiley +1 more source
Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun +5 more
wiley +1 more source
Superficial parasternal intercostal plane block with ropivacaine versus placebo for opioid exposure after cardiac surgery (EPOCH CardioLink-10): a multicentre, double-blind, randomised trial. [PDF]
Alli A +31 more
europepmc +1 more source
The Graphical Abstract summarizes the key concepts of this review, covering supramolecular assembly strategies, CPP material integration, multicolor emission, information encryption, and flexible optoelectronic applications. ABSTRACT Circularly polarized luminescence (CPL) and room‐temperature phosphorescence (RTP) materials are crucial for advanced ...
Wei Zhang +6 more
wiley +1 more source
Day zero of autologous cryopreserved hematopoietic stem cell transplantation: microcosting of care provided by senior nurses. [PDF]
Nunes VAG, Lima AFC.
europepmc +1 more source
ABSTRACT The 1,4,5‐trisphosphate receptor type 1 (ITPR1) gene encodes an endoplasmic reticulum calcium release channel, in which loss‐of‐function mutations have been associated with spinocerebellar ataxias and related neurological phenotypes. Only one gain‐of‐function mutation in the highly conserved suppressor domain of ITPR1 has been previously ...
Emilie T. Théberge +9 more
wiley +1 more source

