Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede +14 more
wiley +1 more source
Predicting the evolution and persistence of COVID-19 using context-dependent polymorphisms. [PDF]
Caraway J, Sung W.
europepmc +1 more source
Nucleus pulposus (NP) and bone marrow derived stem cells (BMSCs) transfected with miRNA‐149‐5p‐mimic and 221‐3p‐inhibitor were evaluated in goat monolayer, microtissue, and ex vivo organ cultures of mild degeneration. miRNA‐treated NP cells demonstrated an anti‐catabolic and pro‐discogenic response in organs, highlighting its potential as a ...
Tara Ní Néill +7 more
wiley +1 more source
Norepinephrine derepresses the Fur regulon of <i>Neisseria gonorrhoeae</i> to enable growth in iron-limited conditions. [PDF]
Westlake CS +8 more
europepmc +1 more source
Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen +8 more
wiley +1 more source
Preliminary Findings of a Chronic Disease Management Program in Medicare Advantage Enrollees with Mild to Moderate Kidney Disease. [PDF]
Morales T +9 more
europepmc +1 more source
ABSTRACT Microfluidic affinity‐based capture of extracellular vesicles (EVs) holds great promise for disease diagnostics and monitoring therapeutic EV production. However, optimizing microfluidic channel geometries for efficient EV capture remains understudied due to the effort required to experimentally test numerous designs.
Arvin Lim +6 more
wiley +1 more source
Mechanized wide narrow row densification configuration enhances japonica rice yield and head rice quality in Northern China. [PDF]
Dong L +5 more
europepmc +1 more source
Large Language Models for Explainable Medical Text Summarization: A Systematic Literature Review
The graphical abstract highlights the three key aspects addressed in this review: the technical background of medical text summarization methods relevant to clinical decision support; the LLM background in providing context for its diagnosis and clinical significance; and clinical decision support with summarization and explainability in patient care ...
Aleka Melese Ayalew +3 more
wiley +1 more source
Monocytes and neutrophils promote cardiac fibroblast pro-fibrotic phenotypes through IL-6 and MIF. [PDF]
Cong Z, Ivetic A, Parsons M.
europepmc +1 more source

