Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster +11 more
wiley +1 more source
A recombinant spider silk protein was functionalized by incorporating genetically encoded bio‐orthogonal reactive azido‐groups. The azido‐functionalized proteins were produced in a scalable biotechnological process, and particles, films, as well as nanofibers were established as anchorage for fully functional antibodies via site‐specific bio‐orthogonal
Claudia Lacombe +4 more
wiley +1 more source
Pharmacokinetics and Customized Dosing of Vancomycin in Adult Patients With Hematological Malignancies: Status, Challenges, and Opportunities. [PDF]
Song X, Zeng M, Yang T, Han M.
europepmc +1 more source
Accelerating real‐world prediction and research in Alzheimer's: The M3AD study
Abstract Chronic diseases, including Alzheimer's disease (AD) and related dementia (ADRD), do not exist solely as isolated entities. Instead, they weave concomitant trajectories of multiple diseases, conditions, behaviors, and risks, mutually influencing each other's course and natural history, in ways yet unexplored.
Moïse Desvarieux +37 more
wiley +1 more source
Common data models and data standards for tabular health data: a systematic review. [PDF]
Finster M, Wenzel M, Taghizadeh E.
europepmc +1 more source
Abstract INTRODUCTION Integrating real‐world data (RWD) with clinical research datasets creates more complete, context‐rich resources to drive discovery and enable precision medicine in Alzheimer's disease and related dementias. The National Alzheimer's Coordinating Center conducted a proof‐of‐concept (POC) project to link its longitudinal Uniform Data
Sarah Biber +23 more
wiley +1 more source
Clinical Decision-Making Case: Febrile Infant. [PDF]
Maupin C, Anand A, Hickam G, Nesbit D.
europepmc +1 more source
Optical and MS characterization of nanoparticles was performed simultaneously through a TDA‐UV/vis‐CDMS setup. The article establishes a new framework for the multimodal characterization of nanoparticles in the ultrahigh mass range. In this new framework, Taylor dispersion analysis (TDA) is integrated with in‐line optical absorbance spectroscopy and ...
Tessa Reinert +7 more
wiley +1 more source
Risk of prostatitis in patients with type 2 diabetes mellitus: An observational retrospective cohort study of canagliflozin versus other antihyperglycemic agents using propensity score matching. [PDF]
Yuan Z +6 more
europepmc +1 more source
Incorporating DAF Into Flocculation Process to Enhance Particle Removal During Intermittent Events
ABSTRACT This study compared a standard Direct Filtration process (DFSTD) with a similar process that incorporated dissolved air flotation into a flocculation basin (DFDAF) to mitigate the effect of particle loading events on filter run time and water quality.
Bilal Abada +4 more
wiley +1 more source

